当前位置: X-MOL 学术Bioinformatics › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
primirTSS: an R package for identifying cell-specific microRNA transcription start sites.
Bioinformatics ( IF 4.4 ) Pub Date : 2020-03-14 , DOI: 10.1093/bioinformatics/btaa173
Pumin Li 1 , Qi Xu 1 , Xu Hua 2 , Zhongwei Xie 1 , Jie Li 1 , Jin Wang 1
Affiliation  

The R/Bioconductor package primirTSS is a fast and convenient tool that allows implementation of the analytical method to identify transcription start sites of microRNAs by integrating ChIP-seq data of H3K4me3 and Pol II. It further ensures the precision by employing the conservation score and sequence features. The tool showed a good performance when using H3K4me3 or Pol II Chip-seq data alone as input, which brings convenience to applications where multiple datasets are hard to acquire. This flexible package is provided with both R-programming interfaces as well as graphical web interfaces.

中文翻译:

primirTSS:一种用于识别细胞特异性microRNA转录起始位点的R包。

R / Bioconductor软件包primirTSS是一种快速便捷的工具,通过整合H3K4me3和Pol II的ChIP-seq数据,可以实施分析方法以鉴定microRNA的转录起始位点。通过使用保守性得分和序列特征,进一步确保了精度。当单独使用H3K4me3或Pol II Chip-seq数据作为输入时,该工具显示出良好的性能,这为难以获取多个数据集的应用程序带来了便利。这个灵活的程序包提供了R编程界面和图形Web界面。
更新日期:2020-03-14
down
wechat
bug