Alcohol consumption and risks of hypertension and cardiovascular disease in Japanese men and women,Hypertension Research

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Alcohol consumption and risks of hypertension and cardiovascular disease in Japanese men and women
Hypertension Research ( IF 4.3 ) Pub Date : 2020-03-13 , DOI: 10.1038/s41440-020-0417-1
Satoyo Ikehara ₁ , Hiroyasu Iso _{1,

2}

Affiliation

This article focuses on selected large prospective cohort studies that examined the effect of alcohol consumption on the risks of hypertension and cardiovascular disease in Japanese men and women. Regardless of age and sex, alcohol consumption was positively associated with an increased risk of hypertension. There was a J-shaped association between alcohol consumption and the risks of stroke and cardiovascular disease in Japanese men, which was consistent with the findings of the studies conducted by Western countries. Few studies have been conducted to examine the effect of alcohol consumption on the risks of stroke and coronary heart disease in Asian women. We first showed that heavy alcohol consumption of ≥300 g ethanol/week was associated with increased risk of total stroke, hemorrhagic stroke, intraparenchymal hemorrhage, subarachnoid hemorrhage and ischemic stroke in women while light drinking was not associated with a reduced risk of stroke. Furthemore, heavy drinking (≥46.0 g ethanol/day) had an increased risk of mortality from coronary heart disease in women, whereas light drinking (0.1–22.9 g ethanol/day) had a reduced risk of mortality from total cardiovascular disease. The association between alcohol consumption and the risk of stroke was modified by social support and salt preference.

中文翻译：

日本男性和女性的饮酒量与高血压和心血管疾病的风险

本文侧重于选定的大型前瞻性队列研究，这些研究检查了饮酒对日本男性和女性高血压和心血管疾病风险的影响。无论年龄和性别如何，饮酒与高血压风险增加呈正相关。日本男性饮酒与中风和心血管疾病风险之间存在 J 型关联，这与西方国家进行的研究结果一致。很少有研究调查饮酒对亚洲女性中风和冠心病风险的影响。我们首先表明，每周 ≥ 300 g 乙醇的大量饮酒与总中风、出血性中风、脑实质出血、女性蛛网膜下腔出血和缺血性中风，而少量饮酒与中风风险降低无关。此外，大量饮酒（≥46.0 克乙醇/天）会增加女性死于冠心病的风险，而少量饮酒（0.1-22.9 克乙醇/天）会降低总体心血管疾病的死亡风险。社会支持和盐偏好改变了饮酒与中风风险之间的关联。

更新日期：2020-03-13

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