Stroke is one of the leading causes of death as well as results in a massive economic burden for society. Stroke is a cerebrovascular disease mainly divided into two types: ischemic stroke and hemorrhagic stroke, which, respectively, refer to the partial blockage and bleeding inside brain blood vessels. Both stroke types lead to nutrient and oxygen deprivation in the brain, which ultimately cause brain damage or death. This study focuses on ischemic stroke in rats with middle cerebral artery occlusion (MCAO) as experimental subjects, and the volumes of infarct and atrophy are calculated based on the brain slice images of rat brains stained with 2,3,5-triphenyl tetrazolium chloride. In this study, a stroke rat brain infarct and atrophy volumes computation system (SRBIAVC system) is developed to segment the infarcts and atrophies from the rat brain slice images. Based on the segmentation results, the infarct and atrophy volumes of a rat brain can be computed. In this study, 168 images of brain slices cut from 28 rat brains with MCAO are used as the test samples. The experimental results show that the segmentation results obtained by the SRBIAVC system are close to those obtained by experts.

中文翻译：

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基于图像的中风大鼠脑萎缩体积和梗死体积计算

中风是导致死亡的主要原因之一，并给社会带来巨大的经济负担。中风是一种脑血管疾病，主要分为缺血性中风和出血性中风两种，分别是指脑血管内部局部堵塞和出血。这两种中风类型都会导致大脑营养和氧气匮乏，最终导致脑损伤或死亡。本研究以大脑中动脉闭塞（MCAO）大鼠缺血性脑卒中为实验对象，根据2,3,5-三苯基氯化四唑染色的大鼠脑切片图像计算梗死体积和萎缩体积。在这项研究中，开发了中风大鼠脑梗塞和萎缩体积计算系统（SRBIAVC 系统）以从大鼠脑切片图像中分割梗塞和萎缩。根据分割结果，可以计算出大鼠大脑的梗塞和萎缩体积。在这项研究中，从 28 只具有 MCAO 的大鼠大脑中切下的 168 幅脑切片图像用作测试样本。实验结果表明，SRBIAVC系统得到的分割结果与专家得到的结果接近。