A series of new dihydrobenzooxophosphole-based Lewis base organocatalysts were designed and synthesized. They are shown to be effective in trichlorosilane-mediated stereoselective conjugate reductions of C=C bonds. DFT calculations reveal that the strong hydrogen bonds between the amide linker and the chloride on silicon in the transition state contribute to the high reactivity of the catalyst.

中文翻译：

---

新型二氢苯并氧代膦基路易斯碱有机催化剂的合理设计

设计并合成了一系列新型二氢苯并氧代膦基路易斯碱有机催化剂。它们被证明在三氯硅烷介导的 C=C 键的立体选择性共轭还原中是有效的。DFT 计算表明，在过渡态的硅上的酰胺接头和氯化物之间的强氢键有助于催化剂的高反应性。