Background

Contaminations of benzo[a]pyrene (B[a]p) in food is the main source of B[a]p exposure to humans. B[a]p as one of the most studied polycyclic aromatic hydrocarbon (PAH) omnipresent in the environment and food. Bifidobacteria and lactic acid bacteria (LAB) now have been used to study the elimination of carcinogenic contaminants of food via stable physical binding.

Scope and approach

The current theoretical study revealed that biological detoxification of B[a]p is an environmentally friendly and cost-effective method. Data was collected by “web of science”, “research gate”, “google scholar”, BJFU online library etc. The aim of this study was to discuss the efficiency of probiotic and LAB cells in in-vitro binding with B[a]p and in in-vivo anti-carcinogenicity and anti-mutagenicity against B[a]p and the whole overview of detoxification mechanism in the food system. To the best we know, this is the first review that focuses on the approaches of probiotic and LABs in the removal of B[a]p. This research will be utilized in the food industrial processing and in the industries that use the “probiotic cell technology” such as pharmaceutical, food, feed etc.

Key findings and conclusions

This study established that B[a]p binding percentage of probiotic and LAB cells were double comparatively non-LAB cells after a critical comparison. It was found that probiotic and LAB cells were effective in in-vivo removal of B[a]p on oral administration and also effective in removal of B[a]p from the food systems. It was concluded that probiotic strains were highly efficient in the removal of B[a]p also having no toxic effects and potential adverse health effects.

中文翻译：

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益生菌和乳酸菌在苯并[a] de解毒中的潜在抗癌作用：综述

背景

食物中苯并[a] re（B [a] p）的污染是人类接触B [a] p的主要来源。B [a] p是在环境和食物中无所不在的研究最多的多环芳香烃（PAH）之一。双歧杆菌和乳酸菌（LAB）现在已用于研究通过稳定的物理结合消除食物的致癌污染物。

范围和方法

当前的理论研究表明，B [a] p的生物排毒是一种环境友好且具有成本效益的方法。数据通过“科学网络”，“研究之门”，“谷歌学者”，BJFU在线图书馆等收集。本研究的目的是讨论益生菌和LAB细胞在体外与B [a]结合的效率。 p以及体内对B [a] p的抗致癌性和致突变性，以及食物系统中的解毒机理的整体概述。据我们所知，这是第一篇侧重于益生菌和LAB去除B [a] p的方法的综述。这项研究将用于食品工业加工以及使用“益生菌技术”的行业，例如制药，食品，饲料等。

主要发现和结论

这项研究确定了关键的比较后，益生菌和LAB细胞的B [a] p结合百分比是非LAB细胞的两倍。发现益生菌和LAB细胞在口服施用中有效去除体内的B [a] p，并且还有效去除食品系统中的B [a] p。结论是，益生菌菌株在去除B [a] p方面非常有效，也没有毒性作用和潜在的不利健康影响。