Pyridyl benzothiazole hydrazone derivatives containing ruthenium, rhodium and iridium complexes have been synthesized, characterized and evaluated for antimicrobial activity. Metal precursors of the type [(arene)RuCl₂]₂(arene = p-cymene, benzene), [Cp*MCl₂]₂ (M = Rh/Ir) and pyridyl benzothiazole hydrazone ligands (L1 and L2) have been employed in this work. Complexes containing ligands L1 in 1:2 (M:L) ratio yielded only one type of cationic mononuclear complexes whereas ligand L2 in 1:2 (M:L) ratio yielded two types of cationic mononuclear complexes. In same manner ligand L2 in 1:1 (M:L) ratio also yielded two types of binuclear complexes with different modes of binding. All these complexes have been characterized by analytical, spectroscopic and single-crystal X-ray diffraction studies. Antibacterial studies of ligands and complexes have been carried out and were found to exhibit potent activity towards gram-positive and gram-negative bacteria.

合成了含钌，铑和铱配合物的吡啶基苯并噻唑衍生物，表征并评估了其抗菌活性。类型为[（arene）RuCl ₂ ] _2的金属前体（亚芳基= 对苯甲基，苯），[Cp * MCl ₂ ] ₂（M = Rh / Ir）和吡啶基苯并噻唑配体（L1和L2）已用于这项工作。含有1：2（M：L）比的配体L1的配合物仅产生一种类型的阳离子单核配合物，而含有1：2（M：L）比例的配体L2产生两种类型的阳离子单核配合物。以相同的方式，配体L2以1：1（M：L）的比例也产生两种类型的具有不同结合方式的双核复合物。所有这些配合物均已通过分析，光谱和单晶X射线衍射研究进行了表征。已经进行了配体和复合物的抗菌研究，发现它们对革兰氏阳性和革兰氏阴性细菌表现出有效的活性。