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Preparation of block copolymer of poly(trimethylene carbonate) with oligo(ethylene glycol) and the surface properties of the dip coated film
Polymer Testing ( IF 5.0 ) Pub Date : 2020-06-01 , DOI: 10.1016/j.polymertesting.2020.106484
Yoshiaki Haramiishi , Ryo Kawatani , Nalinthip Chanthaset , Hiroharu Ajiro

Abstract To persuade the stent coating materials for the better sustainable development, a block copolymer composed of hydrophobicity of poly(trimethylene carbonate) (PTMC) and hydrophilicity of PTMC bearing ethylene glycol chains was synthesized as a potential candidate. The result of thermal stability of the polymer was analyzed which reached up to 206 °C (T10) and it is considered that sufficient for sterilization during the treatment. Moreover, the dip coated films of polymer were coated on polyethylene (PE) and stainless steel (SS) substrates in order to stimulate the stability upon the physiological environment. In addition, the preliminary in vitro test of the films were evaluated by protein adsorption and blood platelet adhesion tests. Hence, this study tends to convince that the synthetic block copolymer based on PTMC derivatives were approached for stent coating materials.

中文翻译:

聚(三亚甲基碳酸酯)与低聚(乙二醇)嵌段共聚物的制备及浸涂膜的表面性能

摘要 为使支架涂层材料更好地可持续发展,合成了具有疏水性的聚(三亚甲基碳酸酯)(PTMC)和亲水性的带有乙二醇链的 PTMC 的嵌段共聚物作为潜在的候选材料。分析了聚合物的热稳定性结果,达到 206°C (T10),认为足以在处理过程中进行灭菌。此外,将聚合物浸涂膜涂覆在聚乙烯 (PE) 和不锈钢 (SS) 基材上,以刺激生理环境的稳定性。此外,通过蛋白质吸附和血小板粘附试验对膜的初步体外试验进行了评价。因此,
更新日期:2020-06-01
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