当前位置: X-MOL 学术BMC Pulm. Med. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Dietary patterns and asthma among Peruvian children and adolescents
BMC Pulmonary Medicine ( IF 2.6 ) Pub Date : 2020-03-14 , DOI: 10.1186/s12890-020-1087-0
Carla E. Tarazona-Meza , Corrine Hanson , Suzanne L. Pollard , Karina M. Romero Rivero , Rocio M. Galvez Davila , Sameera Talegawkar , Carlos Rojas , Jessica L. Rice , William Checkley , Nadia N. Hansel

Asthma is one of the conditions that contributes to the global burden of respiratory diseases and has been previously associated with diet intake. The goal of this study was to determine the relationship between diet, assessed by a developed score, and asthma in Peruvian children. This study was a cross sectional analysis nested within an unmatched case-control study of children in two peri-urban communities of Lima, Peru. We evaluated 767 children and adolescents (573 with asthma, 194 controls) between 9 and 19 years. Diet was assessed using a food frequency questionnaire (FFQ), with food groups classified as “healthy” or “unhealthy”. Asthma control, Lung function and atopy were assessed by Asthma Control Test, Spirometry and InmunoCAP 250 test, respectively. Mean age of participants was 13.8 years (SD 2.6). Mean diet score was 5 (SD 1.23; range 2–8). Healthy Diet Score was associated with asthma status [OR 0.83, 95% CI (0.72, 0.95), p = 0.009] in adjusted analysis. Thus, participants with higher HDS, had lower odds of asthma. In sensitivity analyses, when adjusting for atopy, results did not change significantly. [OR 0.85, 95% CI (0.72, 0.99); p = 0.04]. No association between the HDS and asthma control, FEV1, nor FeNO were observed. Atopy did not modify the association between diet and asthma outcomes. In our study cohort, better diet quality was associated with lower odds of asthma, but was not associated with asthma control. Diet modification may be a potential intervention to impact the increasing prevalence of this disease.

中文翻译:

秘鲁儿童和青少年的饮食习惯和哮喘

哮喘是导致呼吸系统疾病全球负担的疾病之一,以前与饮食摄入有关。这项研究的目的是确定通过发育评分评估的饮食与秘鲁儿童哮喘之间的关系。这项研究是一项横断面分析,嵌套在一项无与伦比的病例对照研究中,该研究针对的是秘鲁利马两个郊区社区的儿童。我们评估了9至19岁之间的767名儿童和青少年(573名哮喘患者,194名对照)。使用食物频率调查表(FFQ)评估饮食,将食物组分类为“健康”或“不健康”。哮喘控制,肺功能和特应性分别通过哮喘控制测试,肺活量测定法和InmunoCAP 250测试进行评估。参与者的平均年龄为13.8岁(SD 2.6)。饮食平均得分为5(SD 1.23; 2-8)。在调整后的分析中,健康饮食评分与哮喘状态相关[OR 0.83,95%CI(0.72,0.95),p = 0.009]。因此,HDS较高的参与者患哮喘的几率较低。在敏感性分析中,当对特应性进行调整时,结果没有明显改变。[OR 0.85,95%CI(0.72,0.99);p = 0.04]。没有观察到HDS与哮喘控制,FEV1和FeNO之间存在关联。特应性并未改变饮食与哮喘结局之间的关联。在我们的研究队列中,饮食质量的改善与哮喘几率降低有关,但与哮喘的控制无关。饮食调整可能是影响这种疾病患病率的潜在干预措施。HDS较高的参与者患哮喘的几率较低。在敏感性分析中,当对特应性进行调整时,结果没有明显改变。[OR 0.85,95%CI(0.72,0.99);p = 0.04]。没有观察到HDS与哮喘控制,FEV1和FeNO之间存在关联。特应性并未改变饮食与哮喘结局之间的关联。在我们的研究队列中,饮食质量的改善与哮喘几率降低有关,但与哮喘的控制无关。饮食调整可能是影响这种疾病患病率的潜在干预措施。HDS较高的参与者患哮喘的几率较低。在敏感性分析中,当对特应性进行调整时,结果没有明显改变。[OR 0.85,95%CI(0.72,0.99);p = 0.04]。没有观察到HDS与哮喘控制,FEV1和FeNO之间存在关联。特应性并未改变饮食与哮喘结局之间的关联。在我们的研究队列中,饮食质量的改善与哮喘几率降低有关,但与哮喘的控制无关。饮食调整可能是影响这种疾病患病率的潜在干预措施。特应性并未改变饮食与哮喘结局之间的关联。在我们的研究队列中,饮食质量的改善与哮喘几率降低有关,但与哮喘的控制无关。饮食调整可能是影响这种疾病患病率的潜在干预措施。特应性并未改变饮食与哮喘结局之间的关联。在我们的研究队列中,饮食质量的改善与哮喘几率降低有关,但与哮喘的控制无关。饮食调整可能是影响这种疾病患病率的潜在干预措施。
更新日期:2020-04-22
down
wechat
bug