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Pseudoduplication of the optic disc initially resembling a bifurcated optic nerve in a strabismus child: a case report
BMC Ophthalmology ( IF 1.7 ) Pub Date : 2020-03-14 , DOI: 10.1186/s12886-020-01369-1
Liuhui Huang , Qi Zhang , Haiying Jin , Peiquan Zhao

Pseudoduplication of the optic disc is a rare clinical condition that is characterized by a circumscribed, disc-like lesion with radiating vessels but only one normal optic nerve. We report a rare case that initially resembled a bifurcated optic nerve in a strabismus child. A 6-year-old female child was initially referred to our hospital due to perceptual exotropia of 15 degrees with poor fixation of the left eye. The visual acuity of the left eye was 3/100 with a refraction of + 1.75/− 1.25 × 175. Fundus images of her left eye revealed a circumscribed and disc-like lesion located one disc diameter (DD) below the true optic disc that showed profound central cupping resembling a second optic disc with a vascular supply. B scan ultrasonography showed an optic nerve with a bifurcated weak-echo region, suggesting that two strands originated from the optic nerve. Optic coherence tomography (OCT) demonstrated a large crater-like depression of the lesion, indicating a colobomatous defect covered by a mysterious membranous structure, a disturbed nerve fibre layer and the absence of regular outer retinal layers. A perimetric examination revealed a relatively superior defect. Magnetic resonance imaging (MRI) revealed the left eye globe showed an abnormal morphology and that the optic nerve was abnormally shaped and shifted nasally in the left eye. Fundus fluorescein angiography (FFA) of the left eye revealed the absence of independent vascular vessels in the disc-like lesion. Hyperfluorescence with patchy fluorescence was evident in the inferotemporal area of the disc. Vascular loops surrounding the temporal region were evident in both eyes. Her right eye was normal except for the vascular loop. We proposed that this represented a case of pseudoduplication of the optic disc. The patient did not undergo any treatment, and her visual acuity remained stable during the follow-up period. Our patient presented with a deep and ectatic coloboma below the optic disc that communicated with the true optic nerve and was originally thought to indicate a bifurcated optic nerve. This case suggests that atypical ectatic colobomas should be considered before diagnosing malformations related to the optic nerve in double optic disc cases.

中文翻译:

最初假发为斜视儿童的视盘伪影重复,类似于分叉的视神经:一例病例报告

视神经盘的假复制是一种罕见的临床疾病,其特征是具有放射血管的外切盘状病变,但仅一条正常的视神经。我们报告了一种罕见的病例,最初是一个斜视儿童的分叉视神经。最初,一名6岁女婴因15度知视性外斜视而被送往我院,左眼注视不佳。左眼的视力为3/100,屈光度为+ 1.75 /-1.25×175。她的左眼眼底图像显示,位于真实视盘下方一个视盘直径(DD)的外切性盘状病变。表现出深刻的中央拔罐,类似于带有血管供应的第二个视盘。B超检查显示视神经具有分叉的弱回声区,提示两条线起源于视神经。光学相干断层扫描(OCT)显示病变处有一个大的坑状凹陷,表明该球状缺损被神秘的膜状结构覆盖,神经纤维层受到干扰,并且没有规则的外部视网膜层。视野检查发现相对较好的缺损。磁共振成像(MRI)显示左眼球体形态异常,左眼的视神经形状异常并向鼻侧移位。左眼的眼底荧光素血管造影(FFA)显示,椎间盘状病变中没有独立的血管。在椎间盘的颞下区域明显出现斑块状荧光。两只眼睛都可见颞部周围的血管环。她的右眼除血管loop外正常。我们提出,这代表了光盘假复制的情况。该患者未接受任何治疗,其视力在随访期间保持稳定。我们的患者在与真正的视神经沟通的视盘下方呈现深部和直肠结肠炎,最初被认为是指示分叉的视神经。这种情况表明,在双视盘病例中,在诊断与视神经相关的畸形之前,应考虑非典型直肠癌。我们的患者在与真正的视神经沟通的视盘下方呈现深部和直肠结肠炎,最初被认为是指示分叉的视神经。这种情况表明,在双视盘病例中,在诊断与视神经相关的畸形之前,应考虑非典型直肠癌。我们的患者在与真正的视神经沟通的视盘下方呈现深部和直肠结肠炎,最初被认为是指示分叉的视神经。这种情况表明,在双视盘病例中,在诊断与视神经相关的畸形之前,应考虑非典型直肠癌。
更新日期:2020-03-16
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