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Evaluation of choroidal thickness, macular thickness, and aqueous flare after cataract surgery in patients with and without diabetes: a prospective randomized study
BMC Ophthalmology ( IF 1.7 ) Pub Date : 2020-03-14 , DOI: 10.1186/s12886-020-01371-7
Yasuko Ikegami , Miyuki Takahashi , Kana Amino

In diabetic eyes, various choroidal abnormalities are noted in addition to changes in the retinal circulation, and the risk of increased aqueous flare and retinal thickening after cataract surgery is higher in diabetic eyes. Inflammation caused by surgery induces breakdown of the blood-retinal barrier and affects the retina, although the influence on the choroid is unknown. Several researchers have evaluated the choroidal thickness (CT) after cataract surgery in patients with diabetes; however, the results are inconsistent. The purpose of this study was to evaluate the influence of uneventful small-incision phacoemulsification cataract surgery on the subfoveal choroidal thickness (SCT), the central macular thickness (CMT), and aqueous flare in patients with diabetes. This study included 59 randomly selected eyes (33 eyes of patients with diabetes and 26 eyes of control patients without diabetes) undergoing small-incision cataract surgery. Among the diabetic eyes, 26 were without diabetic retinopathy, and the remaining eyes had non-proliferative diabetic retinopathy. Aqueous flare, CMT, and SCT measurements were performed before and at 1 week, 1 month, and 3 months after surgery. The postoperative CMT continued to increase significantly until 3 months in both groups. Although the CMT was more in patients with diabetes than in patients without diabetes during the follow-up period, there was no significant difference between the two groups. The aqueous flare value increased until 3 months after surgery in both groups. Although the increase was significant at 3 months after surgery in patients with diabetes, the increase in controls was not significant. The aqueous flare values differed significantly between the two groups before and at 3 months after surgery. There was no significant within-group or between-group difference in pre- and postoperative SCT values. In diabetic eyes with early stage of retinopathy, even small-incision cataract surgery can induce increased aqueous flare and macular thickening until 3 months, although there is no significant change in the choroidal thickness. Further studies are essential to evaluate choroidal changes after the cataract surgery in diabetic eyes.

中文翻译:

白内障手术后糖尿病患者和非糖尿病患者脉络膜厚度,黄斑厚度和房水扩张的评估:一项前瞻性随机研究

在糖尿病眼中,除视网膜循环改变外,还注意到各种脉络膜异常,并且在白内障手术后,糖尿病患者眼底水肿和视网膜增厚的风险更高。尽管对脉络膜的影响尚不清楚,但由外科手术引起的炎症会引起血视网膜屏障的破坏并影响视网膜。几位研究人员评估了糖尿病患者白内障手术后的脉络膜厚度(CT)。但是,结果不一致。这项研究的目的是评估无障碍小切口超声乳化白内障手术对糖尿病患者的中心凹脉络膜厚度(SCT),中央黄斑厚度(CMT)和房水耀斑的影响。这项研究包括59例随机接受小切口白内障手术的眼睛(糖尿病患者为33眼,非糖尿病患者为26眼)。在糖尿病眼中,有26例没有糖尿病性视网膜病变,其余的眼睛具有非增生性糖尿病性视网膜病变。在手术前和手术后1周,1个月和3个月进行水火炬,CMT和SCT测量。两组患者术后CMT持续显着增加直至3个月。尽管在随访期间糖尿病患者的CMT高于非糖尿病患者,但两组之间无显着差异。两组患者的水火光值均增加至手术后3个月。尽管糖尿病患者术后3个月的增加显着,控件的增加并不明显。两组患者术前和术后3个月的房水耀斑值差异显着。术前和术后SCT值在组内或组间无显着差异。在视网膜病变早期的糖尿病眼中,即使脉络膜厚度没有明显改变,即使是小切口白内障手术也可引起房水发作和黄斑增厚,直至3个月。进一步的研究对于评估糖尿病性白内障手术后脉络膜的变化至关重要。在视网膜病变早期的糖尿病眼中,即使脉络膜厚度没有明显变化,即使是小切口白内障手术也可引起房水发作和黄斑增厚,直至3个月。进一步的研究对于评估糖尿病性白内障手术后脉络膜的变化至关重要。在视网膜病变早期的糖尿病眼中,即使脉络膜厚度没有明显变化,即使是小切口白内障手术也可引起房水发作和黄斑增厚,直至3个月。进一步的研究对于评估糖尿病性白内障手术后脉络膜的变化至关重要。
更新日期:2020-03-16
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