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Rapid formation and rupture of an infectious basilar artery aneurysm from meningitis following suprasellar region meningioma removal: a case report.
BMC Neurology ( IF 2.2 ) Pub Date : 2020-03-14 , DOI: 10.1186/s12883-020-01673-9
Xu Wang 1 , Ge Chen 1 , Mingchu Li 1 , Jiantao Liang 1 , Hongchuan Guo 1 , Gang Song 1 , Yuhai Bao 1
Affiliation  

Infectious basilar artery (BA) aneurysm has been occasionally reported to be generated from meningitis following transcranial operation. However, infectious BA aneurysm formed by intracranial infection after endoscopic endonasal operation has never been reported. A 53-year-old man who was diagnosed with suprasellar region meningioma received tumor removal via endoscopic endonasal approach. After operation he developed cerebrospinal fluid (CSF) leak and intracranial infection. The patient ultimately recovered from infection after anti-infective therapy, but a large fusiform BA aneurysm was still formed and ruptured in a short time. Interventional and surgical measures were impossible due to the complicated shape and location of aneurysm and state of his endangerment, therefore, conservative anti-infective therapy was adopted as the only feasible method. Unfortunately, the aneurysm did not disappear and the patient finally died from repeating subarachnoid hemorrhage (SAH). Though extremely rare, it was emphasized that infectious aneurysm can be formed at any stage after transnasal surgery, even when the meningitis is cured. Because of the treatment difficulty and poor prognosis, it was recommended that thorough examination should be timely performed for suspicious patient to make correct diagnosis and avoid fatal SAH.

中文翻译:

脑膜上瘤区脑膜瘤切除后脑膜炎引起的感染性基底动脉瘤快速形成和破裂:1例。

据报道,经颅手术后脑膜炎可引起感染性基底动脉(BA)动脉瘤。然而,内窥镜鼻内镜手术后颅内感染形成的感染性BA动脉瘤尚未见报道。一名53岁的被诊断患有上鞍区脑膜瘤的男子通过内窥镜鼻内镜手术切除了肿瘤。手术后,他出现了脑脊液(CSF)泄漏和颅内感染。经过抗感染治疗后,患者最终从感染中恢复过来,但仍在短时间内形成大梭状BA动脉瘤并破裂。由于动脉瘤的形状和位置复杂且处于危险状态,因此无法进行干预和手术措施,因此,保守的抗感染治疗是唯一可行的方法。不幸的是,动脉瘤没有消失,患者最终因反复蛛网膜下腔出血(SAH)死亡。尽管极为罕见,但要强调的是,即使经脑膜炎治愈,经鼻手术后的任何阶段都可能形成感染性动脉瘤。由于治疗困难和预后不良,建议对可疑患者及时进行彻底检查,以正确诊断并避免致命的SAH。
更新日期:2020-03-16
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