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Conversion from electrocardiosignals to equivalent electrical sources on heart surface.
BMC Bioinformatics ( IF 2.9 ) Pub Date : 2020-03-11 , DOI: 10.1186/s12859-020-3354-8
G V Zhikhareva 1 , Mikhail N Kramm 1 , O N Bodin 2 , Ralf Seepold 3, 4 , Natividad Martinez Madrid 4, 5 , A I Chernikov 1 , Y A Kupriyanova 1 , N A Zhuravleva 1
Affiliation  

The actual task of electrocardiographic examinations is to increase the reliability of diagnosing the condition of the heart. Within the framework of this task, an important direction is the solution of the inverse problem of electrocardiography, based on the processing of electrocardiographic signals of multichannel cardio leads at known electrode coordinates in these leads (Titomir et al. Noninvasiv electrocardiotopography, 2003), (Macfarlane et al. Comprehensive Electrocardiology, 2nd ed. (Chapter 9), 2011). In order to obtain more detailed information about the electrical activity of the heart, we carry out a reconstruction of the distribution of equivalent electrical sources on the heart surface. In this area, we hold reconstruction of the equivalent sources during the cardiac cycle at relatively low hardware cost. ECG maps of electrical potentials on the surface of the torso (TSPM) and electrical sources on the surface of the heart (HSSM) were studied for different times of the cardiac cycle. We carried out a visual and quantitative comparison of these maps in the presence of pathological regions of different localization. For this purpose we used the model of the heart electrical activity, based on cellular automata. The model of cellular automata allows us to consider the processes of heart excitation in the presence of pathological regions of various sizes and localization. It is shown, that changes in the distribution of electrical sources on the surface of the epicardium in the presence of pathological areas with disturbances in the conduction of heart excitation are much more noticeable than changes in ECG maps on the torso surface.

中文翻译:

从心电信号转换为心脏表面的等效电源。

心电图检查的实际任务是提高诊断心脏状况的可靠性。在这项任务的框架内,一个重要的方向是解决心电图逆问题,基于在这些导联中已知电极坐标处处理多通道心脏导联的心电图信号(Titomir等人。Noninvasiv electrocardiotopography,2003),( Macfarlane 等人,《综合心电学》,第二版(第 9 章),2011 年。为了获得有关心脏电活动的更详细信息,我们对心脏表面等效电源的分布进行了重建。在这一领域,我们以相对较低的硬件成本重建心动周期期间的等效源。研究了心动周期不同时间躯干表面电位 (TSPM) 和心脏表面电源 (HSSM) 的心电图。我们在存在不同定位的病理区域的情况下对这些图进行了视觉和定量比较。为此,我们使用基于细胞自动机的心电活动模型。元胞自动机模型使我们能够考虑在存在不同大小和定位的病理区域的情况下心脏兴奋的过程。结果表明,在存在心脏兴奋传导干扰的病理区域的情况下,心外膜表面电源分布的变化比躯干表面心电图图的变化更明显。
更新日期:2020-03-16
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