m7GHub: deciphering the location, regulation and pathogenesis of internal mRNA N7-methylguanosine (m7G) sites in human.,Bioinformatics

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m7GHub: deciphering the location, regulation and pathogenesis of internal mRNA N7-methylguanosine (m7G) sites in human.
Bioinformatics ( IF 4.4 ) Pub Date : 2020-03-12 , DOI: 10.1093/bioinformatics/btaa178
Bowen Song ₁ , Yujiao Tang _{1,

2} , Kunqi Chen _{1,

3} , Zhen Wei _{1,

3} , Rong Rong _{1,

3} , Zhiliang Lu _{1,

3} , Jionglong Su ₄ , João Pedro de Magalhães ₃ , Daniel J Rigden ₂ , Jia Meng _{1,

3,

5}

Affiliation

Recent progress in N7-methylguanosine (m⁷G) RNA methylation studies has focused on its internal (rather than capped) presence within mRNAs. Tens of thousands of internal mRNA m⁷G sites have been identified within mammalian transcriptomes, and a single resource to best share, annotate and analyze the massive m⁷G data generated recently are sorely needed.

中文翻译：

m7GHub：解释人类内部mRNA N7-甲基鸟苷（m7G）位点的位置，调控和发病机理。

N7-甲基鸟苷（m ⁷ G）RNA甲基化研究的最新进展集中在其在mRNA中的内部（而不是加帽的）存在。在哺乳动物转录组中已鉴定出数万个内部mRNA m ⁷ G位点，因此迫切需要一种资源来最佳地共享，注释和分析最近生成的大量m ⁷ G数据。

更新日期：2020-03-12

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