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PIN-LIKES Coordinate Brassinosteroid Signaling with Nuclear Auxin Input in Arabidopsis thaliana.
Current Biology ( IF 8.1 ) Pub Date : 2020-03-12 , DOI: 10.1016/j.cub.2020.02.002
Lin Sun 1 , Elena Feraru 1 , Mugurel I Feraru 1 , Sascha Waidmann 1 , Wenfei Wang 2 , Gisele Passaia 3 , Zhi-Yong Wang 3 , Krzysztof Wabnik 4 , Jürgen Kleine-Vehn 1
Affiliation  

Auxin and brassinosteroids (BR) are crucial growth regulators and display overlapping functions during plant development. Here, we reveal an alternative phytohormone crosstalk mechanism, revealing that BR signaling controls PIN-LIKES (PILS)-dependent nuclear abundance of auxin. We performed a forward genetic screen for imperial pils (imp) mutants that enhance the overexpression phenotypes of PILS5 putative intracellular auxin transport facilitator. Here, we report that the imp1 mutant is defective in the BR-receptor BRASSINOSTEROID INSENSITIVE 1 (BRI1). Our set of data reveals that BR signaling transcriptionally and post-translationally represses the accumulation of PILS proteins at the endoplasmic reticulum, thereby increasing nuclear abundance and signaling of auxin. We demonstrate that this alternative phytohormonal crosstalk mechanism integrates BR signaling into auxin-dependent organ growth rates and likely has widespread importance for plant development.

中文翻译:


PIN-LIKES 在拟南芥中协调油菜素类固醇信号传导与核生长素输入。



生长素和油菜素类固醇 (BR) 是重要的生长调节剂,在植物发育过程中表现出重叠的功能。在这里,我们揭示了另一种植物激素串扰机制,揭示了 BR 信号控制 PIN-LIKES (PILS) 依赖的生长素核丰度。我们对 Imperial pils (imp) 突变体进行了正向遗传筛选,该突变体增强了 PILS5 假定的细胞内生长素转运促进剂的过表达表型。在此,我们报告 imp1 突变体在 BR 受体油菜甾醇不敏感 1 (BRI1) 中存在缺陷。我们的一组数据表明,BR 信号传导转录和翻译后抑制 PILS 蛋白在内质网的积累,从而增加细胞核丰度和生长素信号传导。我们证明,这种替代性植物激素串扰机制将 BR 信号整合到生长素依赖性器官生长速率中,并且可能对植物发育具有广泛的重要性。
更新日期:2020-03-12
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