A series of twelve novel 2-aryl-3-phenyl-2,3,5,6-tetrahydro-4H-1,3-thiazin-4-ones was prepared at room temperature by T3P-mediated cyclization of C-aryl-N-phenyl imines with 3-mercaptopropionic acid. The reaction can also be run as a 3-component reaction, forming the imine in situ. The reactions were operationally simple, rapid and gave yields as high as 75%. This provides ready access to C-aryl-N-phenyl compounds in this family, which have been generally difficult to prepare.

中文翻译：

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T3P促进的一系列新型2-Aryl-3-phenyl-2,3,5,6-tetrahydro-4 H -1,3-thiazin-4-ones的合成

在室温下，通过T3P介导的C-芳基-的环化反应，制备了一系列十二种新颖的2-芳基-3-苯基-2,3,5,6-四氢-4 H -1,3-噻嗪-4-酮N-苯基亚胺与3-巯基丙酸。该反应也可以作为3-组分反应进行，原位形成亚胺。反应操作简单，迅速，产率高达75％。这提供了通常难以制备的该族中的C-芳基-N-苯基化合物的容易获得的途径。