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Symptomatic hemiparkinsonism due to extensive middle and posterior fossa arachnoid cyst: case report.
BMC Neurology ( IF 2.2 ) Pub Date : 2020-03-12 , DOI: 10.1186/s12883-020-01670-y
Bernadette Wimmer 1, 2 , Stephanie Mangesius 1, 3 , Klaus Seppi 1, 4 , Sarah Iglseder 1 , Franziska Di Pauli 1 , Martin Ortler 5 , Elke Gizewski 3, 4 , Werner Poewe 1, 4 , Gregor Karl Wenning 1
Affiliation  

Intracranial neoplasms are an uncommon cause of symptomatic parkinsonism. We here report a patient with an extensive middle and posterior fossa arachnoid cyst presenting with parkinsonism that was treated by neurosurgical intervention. Retrospective chart review and clinical examination of the patient. This 55-year-old male patient with hemiparkinsonism and recurrent bouts of headaches was first diagnosed in 1988. CT scans revealed multiple cystic lesions compressing brainstem and basal ganglia, which were partially resected. Subsequently, the patient was free of complaints for 20 years. In 2009 the patient presented once more with severe unilateral tremor and thalamic pain affecting the right arm. Despite symptomatic treatment with L-Dopa and pramipexole symptoms worsened over time. In 2014 there was further progression with increasing hemiparkinsonism, hemidystonia, unilateral thalamic pain and pyramidal signs. Repeat CT scanning revealed a progression of the cysts as well as secondary hydrocephalus. Following repeat decompression of the brainstem and fenestration of all cystic membranes parkinsonism improved with a MDS- UPDRS III score reduction from 39 to 21. Histology revealed arachnoid cystic material. We report on a rare case of recurrent symptomatic hemiparkinsonism resulting from arachnoid cysts.

中文翻译:

广泛的中,后颅窝蛛网膜囊肿引起的症状性半帕金森综合征:病例报告。

颅内肿瘤是症状性帕金森病的罕见原因。我们在这里报告了一名患者,该患者患有广泛的中,后颅窝蛛网膜囊肿,表现为帕金森氏症,接受了神经外科手术治疗。回顾性图表审查和患者临床检查。这位55岁的偏瘫并反复发作头痛的男性患者于1988年首次被诊断出。CT扫描显示多发性囊性病变压迫脑干和基底节,部分切除。随后,该患者已连续20年没有投诉。在2009年,患者再次出现严重的单侧震颤和丘脑疼痛,影响了右臂。尽管使用L-Dopa进行对症治疗和普拉克索的症状随时间而恶化。2014年,半帕金森综合症,偏瘫,单侧丘脑痛和锥体束征进一步加剧。重复的CT扫描显示了囊肿以及继发性脑积水的进展。在反复对脑干减压和所有囊性膜的开窗后,MDS-UPDRS III评分从39降低到21,改善了帕金森综合症。组织学显示蛛网膜囊性物质。我们报告了蛛网膜囊肿引起的复发性症状性半帕金森综合征的罕见病例。组织学显示蛛网膜囊性物质。我们报告了蛛网膜囊肿引起的复发性症状性半帕金森综合征的罕见病例。组织学显示蛛网膜囊性物质。我们报告了蛛网膜囊肿引起的复发性症状性半帕金森综合征的罕见病例。
更新日期:2020-03-12
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