Abstract In this study, acid-activated multi-walled carbon nanotubes (AA-MWCNT) and poly(3,4-ethylenedioxythiophene) (PEDOT) were deposited on a pencil graphite electrode (PGE) surface for electrochemical sensing applications. The acid-activated multi-walled carbon nanotube/over-oxidized poly(3,4-ethylenedioxythiophene) modified pencil graphite electrode (AA-MWCNT/OO-PEDOT/PGE) was characterized using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX) and X-ray photoelectron spectroscopy (XPS). The sensing properties of the obtained surface were examined for the voltammetric determination of serotonin in a phosphate buffer solution. The effects of the pH, adsorption time, over-oxidation and polymerization parameters on the electrochemical properties of serotonin were investigated. The effects of possible interfering substances were evaluated. The detection limit was determined to be 0.092 µM based on a signal-to-noise ratio of 3. Analytical applications of AA-MWCNT/OO-PEDOT/PGE were successfully tested for the determination of serotonin in human blood serum samples.

中文翻译：

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使用酸活化多壁碳纳米管 - 过氧化聚（3,4-亚乙基二氧噻吩）改性铅笔石墨电极测定血清素的差分脉冲伏安法

摘要 在这项研究中，酸活化的多壁碳纳米管 (AA-MWCNT) 和聚 (3,4-亚乙基二氧噻吩) (PEDOT) 沉积在铅笔石墨电极 (PGE) 表面上，用于电化学传感应用。酸活化多壁碳纳米管/过氧化聚（3,4-亚乙基二氧噻吩）改性铅笔石墨电极（AA-MWCNT/OO-PEDOT/PGE）使用循环伏安法（CV）、电化学阻抗谱（EIS）表征)、扫描电子显微镜 (SEM)、能量色散 X 射线光谱 (EDX) 和 X 射线光电子能谱 (XPS)。检测所得表面的传感特性，用于磷酸缓冲溶液中血清素的伏安测定。pH值、吸附时间、研究了过氧化和聚合参数对血清素电化学性能的影响。评估了可能的干扰物质的影响。基于 3 的信噪比，检测限确定为 0.092 µM。AA-MWCNT/OO-PEDOT/PGE 的分析应用已成功测试用于测定人血清样品中的血清素。