Weakly acidic zeolites play a role in catalytic reactions, especially for transformation of biomass-derived products, where the control of the selectivity plays a crucial role. This review discusses this topic, having received limited attention in literature, to remark how represent both a scientific and applicative valuable area. The review offers clues for understanding how weak acid sites in zeolites could be an opportunity in some specific cases, but the aim is not to provide a systematic state-of-the-art. Rather, after introducing considerable examples and cases where mild acidity could be important (etherification, esterification, epoxidation and Beckmann rearrangement) and a discussion of the nature of weak acid sites, related to defects, present in Silicalite and how to control their nature/amount, the discussion is centred on a more in-depth analysis of three case examples: i) the effect of introduction of T³⁺ atoms in Silicalite-1, ii) the creation of mesoporosity in Fe-MFI and iii) catalysis by ammonium zeolite forms. HMF (5-hydroxymethyl furfural) etherification reaction is a main reaction discussed.

弱酸性沸石在催化反应中起着重要作用，尤其是对于生物质衍生产品的转化而言，其中选择性的控制起着至关重要的作用。这篇评论讨论了这个话题，在文献中受到了很少的关注，以说明如何代表科学和实用的有价值领域。这篇综述为理解沸石中的弱酸性位点在某些特定情况下如何提供了机会提供了线索，但目的并不是提供系统的最新技术。相反，在介绍了许多示例后，例举了弱酸度很重要的情况（醚化，酯化，环氧化和贝克曼重排），并讨论了与硅铝石中存在的与缺陷有关的弱酸位点的性质以及如何控制其性质/量，Silicalite-1中的³⁺原子，ii）在Fe-MFI中产生介孔性，iii）铵沸石形式的催化作用。HMF（5-羟甲基糠醛）醚化反应是讨论的主要反应。