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Preparation and Biomedical Applications of Multicolor Carbon Dots: Recent Advances and Future Challenges
Particle & Particle Systems Characterization ( IF 2.7 ) Pub Date : 2020-03-11 , DOI: 10.1002/ppsc.201900489
Feng Huo 1, 2 , Pran Gopal Karmaker 1 , Yuhang Liu 1, 2 , Bin Zhao 2, 3 , Xiupei Yang 2
Affiliation  

Multicolor carbon dots (CDs) as an emerging subclass of carbonaceous nanomaterials have inspired intensive attention due to the fascinating fluorogenic properties of quantum dots, exhibiting great potential applications in the biomedical field. In some cases, reported CDs with blue or green fluorescence are not desirable for further biological applications owing to the conflicting background autofluorescence, low penetration, and relatively large damage to biological tissue. However, multicolor CDs that can work in the longer wavelength region are being developed to address this issue by overcoming the autofluorescence from the cellular components (usually in the blue and green range). In this review, the development of multicolor CDs is described comprehensively, including for red‐emissive or NIR‐emissive CDs. Additionally, the preparation methods of multicolor CDs are summarized. Moreover, the factors affecting the luminescence of multicolor CDs are discussed in detail, and the biomedical applications are emphasized from multiple perspectives.

中文翻译:

彩色碳点的制备及其生物医学应用:最新进展和未来挑战

作为碳纳米材料的新兴子类,多色碳点(CD)由于量子点的引人入胜的荧光特性而引起了人们的广泛关注,在生物医学领域具有巨大的潜在应用前景。在某些情况下,由于背景自发荧光,低渗透性以及对生物组织的较大破坏,报告的具有蓝色或绿色荧光的CD对于进一步的生物学应用而言是不希望的。但是,正在开发可以在更长波长范围内工作的多色CD,以克服细胞成分的自发荧光(通常在蓝色和绿色范围内)来解决此问题。在这篇综述中,全面描述了多色CD的开发,包括用于红色或NIR的CD。另外,总结了多色CD的制备方法。此外,详细讨论了影响多色CD发光的因素,并从多个角度强调了生物医学应用。
更新日期:2020-03-11
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