Several in vitro and in vivo studies have investigated if a magnetic resonance imaging (MRI) examination can cause DNA damage in human blood cells. However, the electromagnetic field (EMF) exposure that the cells received in the MR scanner was not sufficiently described. The first studies looking into this could be regarded as hypothesis‐generating studies. However, for further exploration into the role of MRI exposure on DNA integrity, the exposure itself cannot be ignored. The lack of sufficient method descriptions makes the early experiments difficult, if not impossible, to repeat. The golden rule in all experimental work is that a study should be repeatable by someone with the right knowledge and equipment, and this is simply not the case with many of the recent studies on MRI and genotoxicity. Here we discuss what is lacking in previous studies, and how we think the next generation of in vitro and in vivo studies on MRI and genotoxicity should be performed. Bioelectromagnetics. © 2020 Bioelectromagnetics Society.

中文翻译：

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磁共振成像遗传毒性研究中需要的有效暴露方案

多项体外和体内研究已经研究了磁共振成像（MRI）检查是否会导致人血细胞中的DNA损伤。但是，没有充分描述在MR扫描仪中接收到的细胞的电磁场（EMF）暴露。对此进行研究的第一批研究可视为假设生成研究。但是，为了进一步探索MRI暴露对DNA完整性的作用，不能忽略暴露本身。缺乏足够的方法描述，使得早期实验很难甚至不可能重复。所有实验工作的黄金法则是，一项具有适当知识和设备的人应该可以重复进行一项研究，而对于最近有关MRI和遗传毒性的许多研究来说，情况并非如此。在这里，我们讨论了以前的研究中缺少的东西，以及我们认为应该如何进行有关MRI和基因毒性的下一代体外和体内研究。生物电磁学。©2020生物电磁学会。