A woman in her late 20s presented with an asymptomatic hyperpigmentation on the right side of the trunk, right upper arm, and right leg, strictly following the lines of Blaschko (Figure, A and B). A slight atrophy of the hyperpigmented skin was palpable without any signs of induration.

The first onset was in her childhood, at the age of 6 years, with a small hyperpigmentation on the right side of her lower chest remaining stable for years. In her early 20s the area of hyperpigmentation started to spread slowly over the above-mentioned areas and became more and more intense. Intravenous penicillin G therapy with 10 million units 3 times daily over 1 week combined with a UV-A1 phototherapy in 18 sessions with a maximum dose of 40 J/cm² and a cumulative overall dose of 670 J/cm² showed no effects. A punch biopsy was obtained (Figure, C and D).

一名20多岁的女性严格遵循Blaschko的线条，在躯干，右上臂和右腿的右侧出现了无症状的色素沉着（图A和B）。色素沉着的皮肤轻微萎缩，没有硬结的迹象。

第一次发病是在她6岁的童年时期，下胸部右侧的小色素沉着症已稳定多年。在她20多岁初期，色素沉着过度区域开始在上述区域缓慢扩散，并变得越来越强烈。1周内每天进行3次1000万单位的青霉素G静脉注射疗法，在18个疗程中联合UV-A1光疗，最大剂量为40 J / cm ²，累积总剂量为670 J / cm ^2，显示无效果。获得了打孔活检（图C和D）。