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Uncontrolled hypertension in Ethiopia: a systematic review and meta-analysis of institution-based observational studies
BMC Cardiovascular Disorders ( IF 2.0 ) Pub Date : 2020-03-11 , DOI: 10.1186/s12872-020-01414-3
Firehiwot Amare , Bisrat Hagos , Mekonnen Sisay , Bereket Molla

Uncontrolled hypertension is one of the major risk factors of cardiovascular and cerebrovascular diseases. The prevalence of hypertension in Ethiopia is expected to reach up to 30%. The aim of this study was to determine the prevalence of uncontrolled hypertension among hypertensive patients on treatment in Ethiopia. Electronic databases and search engines including EMBASE (Ovid), PubMed/Medline, and Google Scholar were searched for original records in the English language addressing hypertension control in Ethiopia from 2000 to 2018. Data were extracted using a format prepared in Microsoft Excel and exported to STATA 15.0 software for analyses. The study protocol is registered at PROSPERO with reference number ID: CRD42018116336. A total of 13 studies with 5226 hypertension patients were included for systematic review and meta-analysis. The pooled prevalence of uncontrolled hypertension in Ethiopia was 48% (95% confidence interval (CI): 36, 61%). The result of the sub-group analysis, based on the year of publications, revealed that the prevalence of uncontrolled BP was highest in 2016 (63%; CI: 60, 67%) and in 2015 (59%; CI: 53, 65%). Univariate meta-regression revealed that sampling distribution was not a source of heterogeneity for the pooled estimate as well as the sub group analysis. The prevalence of uncontrolled hypertension was high in Ethiopia. This alarming public health issue fuels the ever-increasing cardiovascular and cerebrovascular diseases. The ministry of health has to design a policy and implementation mechanisms to reduce uncontrolled hypertension prevalence and improve awareness on blood pressure control.

中文翻译:

埃塞俄比亚无法控制的高血压:基于机构的观察性研究的系统评价和荟萃分析

高血压不受控制是心血管和脑血管疾病的主要危险因素之一。埃塞俄比亚的高血压患病率预计将达到30%。这项研究的目的是确定埃塞俄比亚高血压患者中无法控制的高血压患病率。在2000年至2018年期间,使用电子数据库和搜索引擎(包括EMBASE(Ovid),PubMed / Medline和Google Scholar)搜索了英语的原始记录,以解决埃塞俄比亚的高血压控制问题。使用Microsoft Excel中准备的格式提取数据并将其导出到STATA 15.0软件进行分析。研究方案已在PROSPERO注册,参考编号ID:CRD42018116336。共纳入13项研究,对5226例高血压患者进行系统评价和荟萃分析。埃塞俄比亚的失控高血压合并患病率为48%(95%置信区间(CI):36、61%)。根据出版年份进行的亚组分析结果显示,不受控制的BP患病率最高,2016年(63%; CI:60,67%)和2015年(59%; CI:53,65) %)。单变量元回归表明,样本分布不是汇总估计以及子组分析的异质性来源。埃塞俄比亚的失控高血压患病率很高。这一令人震惊的公共卫生问题助长了不断增加的心血管和脑血管疾病。卫生部必须设计政策和实施机制,以减少高血压的失控患病率并提高对血压控制的认识。
更新日期:2020-03-12
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