BACKGROUND After breast cancer (BC) diagnosis, work incapacity often occurs among working-age women. We investigated the trajectories of previous and subsequent sickness absence and/or disability pension (SA/DP) days, and risk factors for consistently high levels of future SA/DP among these women. METHODS This longitudinal cohort study included all 3536 women in Sweden aged 19-64 years who received a first BC diagnosis in 2010. Their annual SA/DP net days from 2 years before to 3 years after diagnosis were calculated. SA/DP patterns were depicted by a group-based trajectory model. Logistic regressions were used to calculate odds ratios (ORs) with 95% CIs of >90 or >180 SA/DP days/year. RESULTS Three trajectories of SA/DP days/year were identified: increasing only in year+1 (61% of all), increasing then decreasing in year+3 (30%), and constantly very high (9%). The risk factors associated with annual SA/DP days >90 (long) and >180 days (extreme long) were similar. Factors associated with having >90 SA/DP days for years 1-3 were: stage II (OR, 4.59; 95% CI, 2.98-7.07), stage III+IV (OR, 26.57; 95% CI, 13.52-52.22), prediagnosis SA 1-30 days (OR, 2.73; 95% CI, 1.30-5.70), prediagnosis SA >90 days (OR, 24.52; 95% CI, 12.25-49.08), and prediagnosis DP (OR, 659.97; 95% CI, 292.52->999.99). Conversely, adjusting for prediagnosis SA/DP and stage, sociodemographic factors were not associated with high levels of SA/DP. CONCLUSION After BC diagnosis, SA/DP increased significantly but then decreased. The absolute majority had no SA/DP during year 3. Advanced cancer stage and previous high SA/DP rendered the greatest risk for future high SA/DP. More knowledge is needed for applying the information in rehabilitation and return-to-work planning.

中文翻译：

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乳腺癌诊断前2年和诊断后3年的疾病缺席和残疾抚恤金的轨迹：一项基于瑞典纵向人群的队列研究。

背景技术在乳腺癌（BC）诊断之后，在工作年龄的女性中经常发生工作能力丧失。我们调查了这些妇女先前和随后的疾病缺勤和/或残障抚恤金（SA / DP）天的轨迹，以及未来妇女SA / DP持续较高水平的危险因素。方法这项纵向队列研究纳入了所有3536名瑞典妇女，年龄在19-64岁之间，这些妇女在2010年首次进行了BC诊断。计算了从诊断前2年到诊断后3年的年SA / DP净天数。SA / DP模式由基于组的轨迹模型描绘。Logistic回归用于计算95％CI≥90或> 180 SA / DP天/年的优势比（OR）。结果确定了SA / DP天/年的三种轨迹：仅在第1年增加（占总数的61％），在第3年增加然后减少（占30％），并且一直很高（9％）。与每年SA / DP天> 90天（长）和> 180天（极长）相关的危险因素相似。在1-3年中与> 90 SA / DP天相关的因素是：II期（OR，4.59; 95％CI，2.98-7.07），III + IV期（OR，26.57; 95％CI，13.52-52.22） ，诊断前SA 1-30天（OR，2.73; 95％CI，1.30-5.70），诊断前SA> 90天（OR，24.52; 95％CI，12.25-49.08）和诊断前DP（OR，659.97; 95％ CI，292.25-> 999.99）。相反，调整预诊断SA / DP和分期，社会人口统计学因素与高水平的SA / DP无关。结论BC诊断后，SA / DP明显升高，但随后下降。绝对多数患者在第3年内没有SA / DP。晚期癌症和先前的高SA / DP构成了未来高SA / DP的最大风险。