Near-IR oxime-based solvatochromic perylene diimide probe as a chemosensor for Pd species and Cu2+ ions in water and live cells,Photochemical & Photobiological Sciences

当前位置： X-MOL 学术 › Photochem. Photobiol. Sci. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Near-IR oxime-based solvatochromic perylene diimide probe as a chemosensor for Pd species and Cu2+ ions in water and live cells
Photochemical & Photobiological Sciences ( IF 2.7 ) Pub Date : 2020-03-10 , DOI: 10.1039/c9pp00487d
Poonam Sharma _{1,

2,

3,

4,

5} , Sandeep Kaur _{3,

4,

5,

6} , Satwinderjeet Kaur _{3,

4,

5,

6} , Prabhpreet Singh _{1,

2,

3,

4,

5}

Affiliation

A near-IR perylene diimide probe (OPR-PDI) containing an oxime-propargyl hybrid moiety at the bay position, was designed and synthesized for detection of Pd species and Cu²⁺ ions in 90% water, the solid state and MG-63 live cells. The aggregation tendency of OPR-PDI in different polarity solvents transmits solvatochromic and fluorochromic properties to differentiate certain organic solvents. Supramolecular aggregates of OPR-PDI in 90% water act as a dual chemosensor for palladium (Pd) species via de-propargylation or hydrolysis of the Schiff-base and Cu²⁺ ions via complexation with the O/N binding site with a low limit of detection (LOD) of the order of 7.9 × 10⁻⁸ M and 3.4 × 10⁻⁷ M respectively. TLC strips coated with OPR-PDI can be applied for sensing of Pd⁰ and Cu²⁺ ions in the solid state at levels as low as 34.6 ng cm⁻² and 10.5 ng cm⁻². OPR-PDI imprinted TLC strips could be used as paper sheets for writing coloured alphabets using Pd⁰ and Cu²⁺ ions as ink. Moreover, MTT assay showed that OPR-PDI has very low cytotoxicity (IC₅₀ = 230 μM), good permeability, biocompatibility and can be applied for bio-imaging of Pd species and Cu²⁺ ions in MG-63 cells. DFT calculations, and cyclic voltammetric (CV) and NMR titration studies have also been discussed.

中文翻译：

基于近红外肟的溶剂化变色per二酰亚胺探针作为水和活细胞中Pd物种和Cu2 +离子的化学传感器

设计并合成了在海湾位置包含肟-炔丙基杂化部分的近红外per二酰亚胺探针（OPR-PDI），用于检测90％水中，固态和MG-63中的Pd物种和Cu ²⁺离子活细胞。OPR-PDI在不同极性溶剂中的聚集趋势会传递溶剂变色和荧光变色特性，以区分某些有机溶剂。的超分子聚集OPR-PDI在90％的水充当双重化学传感器为钯（Pd）物种经由解炔丙基或席夫碱的水解和Cu ²⁺离子经由与O / N结合位点的低检出限（LOD）的复合分别为7.9×10 ^-8 M和3.4×10 ^-7 M的数量级。涂有OPR-PDI的TLC条带可用于检测固态Pd ⁰和Cu ²⁺，其水平低至34.6 ng cm ^-2和10.5 ng cm ^-2。印有OPR-PDI的TLC条带可用作纸张，用于使用Pd ⁰和Cu ²⁺离子作为墨水书写彩色字母。此外，MTT分析表明OPR-PDI的细胞毒性非常低（IC ₅₀= 230μM），良好的渗透性，生物相容性，可用于MG-63细胞中Pd物种和Cu ²⁺离子的生物成像。还讨论了DFT计算，循环伏安法（CV）和NMR滴定研究。

更新日期：2020-04-24

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11