Effect of corneal stromal pocket irrigation in small-incision lenticule extraction,Eye

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Effect of corneal stromal pocket irrigation in small-incision lenticule extraction
Eye ( IF 2.8 ) Pub Date : 2020-03-10 , DOI: 10.1038/s41433-020-0840-1
Han Wang _{1,

2} , Hui Ding ₂ , Bo-Wen Ouyang _{1,

2} , Zhenduo Yang ₂ , Tan Zhong ₂ , Hongming Fan ₂ , Xingwu Zhong _{1,

2}

Affiliation

Objectives To investigate the effect of corneal stromal pocket irrigation after small-incision lenticule extraction (SMILE) on visual acuity, intraocular pressure (IOP), corneal parameters and complications after surgery. Methods A total of 242 eyes of 121 patients undergoing SMILE were enrolled in this prospective controlled study, and it was designed for one eye to randomly undergo SMILE with balanced salt solution irrigation of the corneal stromal pocket, while the other eye was not. The uncorrected distance visual acuity (UDVA) and slit lamp examination were recorded at 1 hour, 1 day, 1 week, and 1 month. Postoperative corneal density, corneal biomechanical, corneal endothelial cell number, and anterior OCT images were compared at 1 day, 1 week, and 1 month. Results Compared with the nonirrigation group, the irrigation group showed significantly higher UDVA at 1 day postoperatively ( P < 0.05), but there was no significant difference during the rest of the postoperative period (1 hour, 1 week, and 1 month). In addition, no significant differences were found in IOP, corneal density, corneal biomechanics, corneal endothelial cells, and corneal morphology. No visual decline or severe postoperative complications were found in the patients in this study. Conclusions Interlamellar irrigation did not affect IOP, corneal parameters, morphology, complications, or UDVA at 1 hour, 1 week, and 1 month after the operation, but it may promote UDVA 1 day after the operation.

中文翻译：

角膜基质袋冲洗在小切口微透镜提取中的作用

目的探讨小切口微透镜提取（SMILE）术后角膜基质袋冲洗对视力、眼压（IOP）、角膜参数及术后并发症的影响。方法本前瞻性对照研究纳入121例SMILE患者共242只眼，设计为一只眼随机接受角膜基质袋平衡盐溶液冲洗SMILE，另一只眼不进行SMILE。在 1 小时、1 天、1 周和 1 个月时记录未矫正远视力 (UDVA) 和裂隙灯检查。比较术后 1 天、1 周和 1 个月的术后角膜密度、角膜生物力学、角膜内皮细胞数量和前 OCT 图像。结果与不灌水组相比，灌洗组术后 1 d UDVA 显着升高（ P < 0.05），但术后剩余时间（1 h、1 周、1 个月）无显着差异。此外，在眼压、角膜密度、角膜生物力学、角膜内皮细胞和角膜形态方面没有发现显着差异。本研究中的患者均未发现视力下降或严重的术后并发症。结论层间冲洗对术后1 h、1周、1个月的眼压、角膜参数、形态、并发症及UDVA均无影响，但可促进术后1天的UDVA。在眼压、角膜密度、角膜生物力学、角膜内皮细胞和角膜形态方面没有发现显着差异。本研究中的患者均未发现视力下降或严重的术后并发症。结论层间冲洗对术后1小时、1周、1个月的眼压、角膜参数、形态、并发症及UDVA均无影响，但可促进术后1天的UDVA。在眼压、角膜密度、角膜生物力学、角膜内皮细胞和角膜形态方面没有发现显着差异。本研究中的患者均未发现视力下降或严重的术后并发症。结论层间冲洗对术后1小时、1周、1个月的眼压、角膜参数、形态、并发症及UDVA均无影响，但可促进术后1天的UDVA。

更新日期：2020-03-10

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