Patient-reported outcomes (PROs) refer to patient perceived and reported health-related quality of life (HRQOL), functional status, and symptom burden. PROs have become an important measure in oncologic care to identify the impact of the disease and its treatment on a patient’s health status. Hematopoietic cell transplantation (HCT) is an aggressive and potentially curative therapy for patients with high-risk hematologic malignancies. A common complication of HCT is graft-versus-host disease (GVHD), which can be a significant contributor to morbidity and mortality, as well as a wide spectrum of physical and psychosocial effects. Quality of life and symptom burden have been shown to be important measures in the study of posttransplant complications, including chronic GVHD. We review the need for a novel tool in acute GVHD to capture disease symptoms and HRQOL to better understand patient symptoms, disease trajectory and outcome.

患者报告的结果 (PROs) 是指患者感知和报告的与健康相关的生活质量 (HRQOL)、功能状态和症状负担。PROs 已成为肿瘤护理中确定疾病及其治疗对患者健康状况影响的重要措施。造血细胞移植 (HCT) 是一种针对高危血液系统恶性肿瘤患者的侵袭性和潜在治愈性疗法。HCT 的一个常见并发症是移植物抗宿主病 (GVHD)，它可能是发病率和死亡率以及广泛的身体和心理社会影响的重要因素。生活质量和症状负担已被证明是研究移植后并发症（包括慢性 GVHD）的重要指标。