当前位置: X-MOL 学术Acta Neurochir. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Occurrence and prognostic effect of cervical spine injuries and cervical artery injuries with concomitant severe head injury.
Acta Neurochirurgica ( IF 2.4 ) Pub Date : 2020-03-10 , DOI: 10.1007/s00701-020-04279-9
Juho Vehviläinen 1 , Tuomas Brinck 2 , Matias Lindfors 1 , Jussi Numminen 3 , Jari Siironen 1 , Rahul Raj 1
Affiliation  

BACKGROUND Blunt cerebrovascular injuries (BCVIs) and cervical spinal injuries (CSIs) are not uncommon injuries in patients with severe head injury and may affect patient recovery. We aimed to assess the independent relationship between BCVI, CSI, and outcome in patients with severe head injury. METHODS We identified patients with severe head injury from the Helsinki Trauma Registry treated during 2015-2017 in a large level 1 trauma hospital. We assessed the association between BCVI and SCI using multivariable logistic regression, adjusting for injury severity. Our primary outcome was functional outcome at 6 months, and our secondary outcome was 6-month mortality. RESULTS Of 255 patients with a cervical spine CT, 26 patients (10%) had a CSI, and of 194 patients with cervical CT angiography, 16 patients (8%) had a BCVI. Four of the 16 BCVI patients had a BCVI-related brain infarction, and four of the CSI patients had some form of spinal cord injury. After adjusting for injury severity in multivariable logistic regression analysis, BCVI associated with poor functional outcome (odds ratio [OR] = 6.0, 95% CI [confidence intervals] = 1.4-26.5) and mortality (OR = 7.9, 95% CI 2.0-31.4). We did not find any association between CSI and outcome. CONCLUSIONS We found that BCVI with concomitant head injury was an independent predictor of poor outcome in patients with severe head injury, but we found no association between CSI and outcome after severe head injury. Whether the association between BCVI and poor outcome is an indirect marker of a more severe injury or a result of treatment needs further investigations.

中文翻译:

颈椎损伤和颈动脉损伤伴有严重的颅脑损伤的发生和预后。

背景技术在重型颅脑损伤患者中,钝性脑血管损伤(BCVIs)和颈椎损伤(CSIs)并非罕见,可能会影响患者的康复。我们旨在评估重度颅脑损伤患者的BCVI,CSI和结局之间的独立关系。方法我们从2015年至2017年期间在大型1级创伤医院接受治疗的赫尔辛基创伤登记处确定了严重颅脑损伤患者。我们使用多元logistic回归评估了BCVI和SCI之间的关联,并根据损伤的严重程度进行了调整。我们的主要结局是6个月时的功能性结局,而次要结局是6个月的死亡率。结果在255例颈椎CT患者中,有26例(10%)患有CSI,在194例颈椎CT血管造影患者中,有16例(8%)患有BCVI。16例BCVI患者中有4例患有BCVI相关性脑梗塞,而CSI病例中有4例患有某种形式的脊髓损伤。在多因素logistic回归分析中对伤害严重性进行调整后,BCVI与功能不良(赔率[OR] = 6.0,95%CI [置信区间] = 1.4-26.5)和死亡率(OR = 7.9,95%CI 2.0- 31.4)。我们没有发现CSI与结果之间有任何关联。结论我们发现伴有颅脑损伤的BCVI是严重颅脑损伤患者预后不良的独立预测因子,但我们发现CSI与颅脑严重损伤后预后之间无关联。BCVI与不良预后之间的关联是更严重的损伤的间接标志还是治疗的结果,还需要进一步研究。其中有4名CSI患者患有某种形式的脊髓损伤。在多因素logistic回归分析中对伤害严重性进行调整后,BCVI与功能不良(赔率[OR] = 6.0,95%CI [置信区间] = 1.4-26.5)和死亡率(OR = 7.9,95%CI 2.0- 31.4)。我们没有发现CSI与结果之间有任何关联。结论我们发现伴有颅脑损伤的BCVI是严重颅脑损伤患者预后不良的独立预测因子,但我们发现CSI与颅脑严重损伤后预后之间无关联。BCVI与不良预后之间的关联是更严重的损伤的间接标志还是治疗的结果,还需要进一步研究。其中有4名CSI患者患有某种形式的脊髓损伤。在多因素logistic回归分析中对伤害严重性进行调整后,BCVI与功能不良(赔率[OR] = 6.0,95%CI [置信区间] = 1.4-26.5)和死亡率(OR = 7.9,95%CI 2.0- 31.4)。我们没有发现CSI与结果之间有任何关联。结论我们发现伴有颅脑损伤的BCVI是严重颅脑损伤患者预后不良的独立预测因子,但我们发现CSI与颅脑严重损伤后预后之间无关联。BCVI与不良预后之间的关联是更严重的损伤的间接标志还是治疗的结果,还需要进一步研究。在多因素logistic回归分析中对伤害严重性进行调整后,BCVI与功能不良(赔率[OR] = 6.0,95%CI [置信区间] = 1.4-26.5)和死亡率(OR = 7.9,95%CI 2.0- 31.4)。我们没有发现CSI与结果之间有任何关联。结论我们发现伴有颅脑损伤的BCVI是严重颅脑损伤患者预后不良的独立预测因子,但我们发现CSI与颅脑严重损伤后预后之间无关联。BCVI与不良预后之间的关联是更严重的损伤的间接标志还是治疗的结果,还需要进一步研究。在多因素logistic回归分析中对伤害严重性进行调整后,BCVI与功能不良(赔率[OR] = 6.0,95%CI [置信区间] = 1.4-26.5)和死亡率(OR = 7.9,95%CI 2.0- 31.4)。我们没有发现CSI与结果之间有任何关联。结论我们发现伴有颅脑损伤的BCVI是严重颅脑损伤患者预后不良的独立预测因子,但我们发现CSI与颅脑严重损伤后预后之间无关联。BCVI与不良预后之间的关联是更严重的损伤的间接标志还是治疗的结果,还需要进一步研究。我们没有发现CSI与结果之间有任何关联。结论我们发现伴有颅脑损伤的BCVI是严重颅脑损伤患者预后不良的独立预测因子,但我们发现CSI与颅脑严重损伤后预后之间无关联。BCVI与不良预后之间的关联是更严重的损伤的间接标志还是治疗的结果,还需要进一步研究。我们没有发现CSI与结果之间有任何关联。结论我们发现伴有颅脑损伤的BCVI是严重颅脑损伤患者预后不良的独立预测因子,但我们发现CSI与颅脑严重损伤后预后之间无关联。BCVI和不良预后之间的关联是否是更严重损伤的间接标志或治疗结果还需要进一步研究。
更新日期:2020-03-10
down
wechat
bug