当前位置: X-MOL 学术Best Pract. Res. Clin. Endocrinol. Metab. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Disease monitoring of Primary Aldosteronism.
Best Practice & Research Clinical Endocrinology & Metabolism ( IF 6.1 ) Pub Date : 2020-03-10 , DOI: 10.1016/j.beem.2020.101417
Gian Paolo Rossi 1 , Maurizio Cesari 1 , Livia Lenzini 1 , Teresa M Seccia 1
Affiliation  

Primary aldosteronism (PA) is a highly prevalent cause of arterial hypertension featuring excess cardiovascular events. A timely diagnosis and treatment of PA cures hyperaldosteronism and can provide resolution or improvement of arterial hypertension, even when the latter is resistant to drug treatment. Accordingly, strategies to screen early and widely the hypertensive patients for PA by means of simplified diagnostic algorithms are justified. Such strategies are particularly beneficial in subgroups of hypertensive patients, who are at the highest cardiovascular risk. Broadening of screening strategies means facing with an increased number of patients where monitoring the disease becomes necessary. Hence, after identification of the surgically and non surgically curable cases of PA and implementation of targeted treatment physicians are faced with the challenges of follow-up, which are scantly discussed in the literature. Hence, the purpose of this paper is to provide some recommendations on how to optimize the monitoring of patients in whom the PA subtype has been diagnosed and treatment, either with unilateral laparoscopic adrenalectomy or medically, has been instituted.



中文翻译:

原发性醛固酮增多症的疾病监测。

原发性醛固酮增多症(PA)是动脉高血压的高度普遍原因,其特征是心血管事件过多。及时诊断和治疗PA可以治愈醛固酮增多症,即使高血压对药物治疗有抵抗力,也可以缓解或改善动脉高血压。因此,通过简化的诊断算法来早期和广泛筛选高血压患者的PA的策略是合理的。此类策略在心血管疾病风险最高的高血压患者亚组中特别有益。扩大筛查策略意味着需要监测疾病的患者人数增加。因此,在确定了PA的手术和非手术可治愈病例后,针对性治疗的实施,医生们面临着随访的挑战,这在文献中很少讨论。因此,本文的目的是就如何优化对已诊断为PA亚型并已通过单侧腹腔镜肾上腺切除术或医学治疗的患者的监测提供一些建议。

更新日期:2020-03-10
down
wechat
bug