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T Cell Cytokines Impact Epithelial Cell Responses during Helicobacter pylori Infection
The Journal of Immunology ( IF 3.6 ) Pub Date : 2020-03-09 , DOI: 10.4049/jimmunol.1901307
Holly M. Scott Algood 1
Affiliation  

The goal of this Brief Review is to highlight literature that demonstrates how cytokines made by T lymphocytes impact the gastric epithelium, especially during Helicobacter pylori infection. These cytokines effect many of the diverse functions of the epithelium and the epithelium’s interactions with H. pylori. The focal point of this Brief Review will be on how T cell cytokines impact antimicrobial function and barrier function and how T cell cytokines influence the development and progression of cancer. Furthermore, the modulation of epithelial-derived chemokines by H. pylori infection will be discussed.

中文翻译:

T 细胞因子在幽门螺杆菌感染期间影响上皮细胞反应

本简要综述的目的是突出展示 T 淋巴细胞产生的细胞因子如何影响胃上皮的文献,尤其是在幽门螺杆菌感染期间。这些细胞因子影响上皮的多种不同功能以及上皮与幽门螺杆菌的相互作用。本简要综述的重点将是 T 细胞细胞因子如何影响抗菌功能和屏障功能,以及 T 细胞细胞因子如何影响癌症的发展和进展。此外,还将讨论幽门螺杆菌感染对上皮衍生趋化因子的调节。
更新日期:2020-03-09
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