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Cervical cancer burden in Latin America and the Caribbean: Where are we?
International Journal of Cancer ( IF 5.7 ) Pub Date : 2020-03-09 , DOI: 10.1002/ijc.32956
Sophie Pilleron 1 , Citadel J Cabasag 2 , Jacques Ferlay 2 , Freddie Bray 2 , Silvana Luciani 3 , Maribel Almonte 1 , Marion Piñeros 2
Affiliation  

In May 2018, the World Health Organization (WHO) called for the elimination of cervical cancer. To monitor this initiative, we examined cervical cancer incidence and mortality in the Latin America and Caribbean (LAC) region using GLOBOCAN 2018, Cancer Incidence in Five Continents Series, and the WHO Mortality Database. We estimated the number of cases and age‐standardized rates (ASRs) for cervical cancer incidence and mortality for 2018. We also presented the ASRs for recorded cervical cancer incidence from the period 2008 to 2012. We calculated annual rates and analyzed trends in cervical cancer incidence and mortality for all ages combined and for the following age groups: 0–29, 30–49, 50–64 and 65+. Finally, we calculated the estimated average annual percentage change in incidence and mortality rates for the past 10 years. In 2018, an estimated 56,000 new cervical cancer cases and 28,000 cervical cancer deaths occurred among women in LAC with great variations between subregions and countries/territories. Overall, trends in cervical cancer incidence and mortality have decreased over the past decade; however, the rates are still above the elimination threshold of 4 per 100,000 in most LAC countries/territories. Despite the encouraging trends observed, achieving the elimination of cervical cancer in the region still requests substantial political commitment and economic effort. Population‐based cancer registries are critical in monitoring the elimination initiative.

中文翻译:

拉丁美洲和加勒比地区的子宫颈癌负担:我们在哪里?

2018年5月,世界卫生组织(WHO)呼吁消除宫颈癌。为了监测这一举措,我们使用GLOBOCAN 2018,五大洲癌症发病率系列和WHO死亡率数据库检查了拉丁美洲和加勒比(LAC)地区的宫颈癌发病率和死亡率。我们估计了2018年宫颈癌发病率和死亡率的病例数和年龄标准化率(ASR)。我们还提供了记录的2008年至2012年宫颈癌发病率的ASR。我们计算了年发病率并分析了宫颈癌的趋势所有年龄段以及以下年龄段的总发病率和死亡率:0-29、30-49、50-64和65+。最后,我们计算了过去10年中发病率和死亡率的估计平均每年百分比变化。在2018年,拉美和加勒比地区估计有56,000例新的子宫颈癌病例和28,000例子宫颈癌死亡,各次区域和国家/地区之间存在很大差异。总体而言,在过去十年中,子宫颈癌的发病率和死亡率的趋势有所下降。但是,在大多数拉美和加勒比地区国家/地区,该比率仍高于每100,000个消除阈值4个。尽管观察到令人鼓舞的趋势,但要在该地区消除宫颈癌仍然需要作出巨大的政治承诺和经济努力。基于人群的癌症注册管理机构对于监测消除计划至关重要。在过去的十年中,宫颈癌的发病率和死亡率的趋势有所下降;但是,在大多数拉美和加勒比地区国家/地区,该比率仍高于每100,000个消除阈值4个。尽管观察到令人鼓舞的趋势,但要在该地区消除宫颈癌仍然需要作出巨大的政治承诺和经济努力。基于人群的癌症注册管理机构对于监测消除计划至关重要。在过去的十年中,宫颈癌的发病率和死亡率的趋势有所下降;但是,在大多数拉丁美洲和加勒比国家/地区,该比率仍高于每100,000个消除阈值4个。尽管观察到令人鼓舞的趋势,但要在该地区消除宫颈癌仍然需要作出巨大的政治承诺和经济努力。基于人群的癌症注册管理机构对于监测消除计划至关重要。
更新日期:2020-03-09
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