The blends of poly(1,3‐trimethylene carbonate‐b‐(l‐lactide‐ran‐glycolide)) (PTLG) with poly(d‐lactide) (PDLA) were prepared via solution‐casting method using CH₂Cl₂ as solvent. The poly(l‐lactide) (PLLA) segments of PTLG with PDLA chain constructed as stereocomplex structures and growth stereocomplex crystals of PLA (sc‐PLA). The effects of sc‐PLA crystals on thermal behavior, mechanical properties, thermal decomposition of the PTLG/PDLA blends were investigated, respectively. The differential scanning calorimetry (DSC) and wide‐angle X‐ray diffraction (WAXD) results showed that the total crystallinity of the PTLG/PDLA blends was increased with the PDLA content increasing. Heterogeneous nucleation of sc‐PLA crystals induced crystallization of the PLLA segments in PTLG. The crystallization temperature of samples shifted to 107.5°C for the PTLG/PDLA‐20 blends compared with that of the PTLG matrix, and decreased the half‐time of crystallization. The mechanical measurement results indicated that the tensile strength of the PTLG/PDLA blends was improved from 21.1 MPa of the PTLG matrix to 39.5 MPa of PTLG/PDLA‐20 blends. The results of kinetics of thermal decomposition of the PTLG/PDLA blends by TGA showed that the apparent activation energy of the PTLG/PDLA blends was increased from 59.1 to 72.1 kJ/mol with the increasing of the PDLA content from 3 wt% to 20 wt%, which indicated the enhancement of thermal stability of the PTLG/PDLA blends by addition of PDLA. Furthermore, the biocompatibility of the PTLG/PDLA blends cultured with human adipose‐derived stem cells was evaluated by CCK‐8 and live/dead staining. The experiment results proved the PTLG/PDLA blends were a kind of biomaterial with excellent physical performances with very low cytotoxicity.

中文翻译：

---

通过PDLA / PLLA立体配合物结晶，增强结晶行为以优化Poly（TMC-b-（LLA-ran-GA））的性能

聚的共混物（1,3-三亚甲基碳酸酯b - （升-lactide-跑-glycolide））（PTLG）与聚（d丙交酯）（PDLA）经由使用CH溶液流延方法制备₂氯₂作为溶剂。聚（升具有PDLA链的PTLG的-丙交酯（PLLA）片段被构建为PLA（sc-PLA）的立体复合物结构和生长立体复合物晶体。分别研究了sc-PLA晶体对PTLG / PDLA共混物的热行为，力学性能和热分解的影响。差示扫描量热法（DSC）和广角X射线衍射（WAXD）结果表明，PTLG / PDLA共混物的总结晶度随PDLA含量的增加而增加。sc-PLA晶体的异质成核导致PTLG中PLLA片段的结晶。与PTLG基质相比，PTLG / PDLA-20混合物的样品结晶温度移至107.5°C，并减少了结晶时间。力学测量结果表明，PTLG / PDLA共混物的拉伸强度从PTLG基体的21.1 MPa提高到PTLG / PDLA-20共混物的39.5 MPa。TGA对PTLG / PDLA共混物进行热分解的动力学结果表明，随着PDLA含量从3 wt％增加到20 wt％，PTLG / PDLA共混物的表观活化能从59.1增至72.1 kJ / mol。 ％，这表明通过添加PDLA提高了PTLG / PDLA共混物的热稳定性。此外，通过CCK-8和活/死染色评估了与人类脂肪干细胞一起培养的PTLG / PDLA共混物的生物相容性。实验结果证明，PTLG / PDLA共混物是一种物理性能优异，细胞毒性极低的生物材料。1 MPa的PTLG基质至39.5 MPa的PTLG / PDLA-20混合物。TGA对PTLG / PDLA共混物进行热分解的动力学结果表明，随着PDLA含量从3 wt％增加到20 wt％，PTLG / PDLA共混物的表观活化能从59.1增至72.1 kJ / mol。 ％，这表明通过添加PDLA提高了PTLG / PDLA共混物的热稳定性。此外，通过CCK-8和活/死染色评估了与人类脂肪干细胞一起培养的PTLG / PDLA共混物的生物相容性。实验结果证明，PTLG / PDLA共混物是一种物理性能优良，细胞毒性极低的生物材料。1 MPa的PTLG基质至39.5 MPa的PTLG / PDLA-20混合物。TGA对PTLG / PDLA共混物进行热分解的动力学结果表明，随着PDLA含量从3 wt％增加到20 wt％，PTLG / PDLA共混物的表观活化能从59.1增至72.1 kJ / mol。 ％，这表明通过添加PDLA提高了PTLG / PDLA共混物的热稳定性。此外，通过CCK-8和活/死染色评估了与人类脂肪干细胞培养的PTLG / PDLA共混物的生物相容性。实验结果证明，PTLG / PDLA共混物是一种物理性能优良，细胞毒性极低的生物材料。TGA对PTLG / PDLA共混物进行热分解的动力学结果表明，随着PDLA含量从3 wt％增加到20 wt％，PTLG / PDLA共混物的表观活化能从59.1增至72.1 kJ / mol。 ％，这表明通过添加PDLA提高了PTLG / PDLA共混物的热稳定性。此外，通过CCK-8和活/死染色评估了与人类脂肪干细胞培养的PTLG / PDLA共混物的生物相容性。实验结果证明，PTLG / PDLA共混物是一种物理性能优良，细胞毒性极低的生物材料。TGA对PTLG / PDLA共混物进行热分解的动力学结果表明，随着PDLA含量从3 wt％增加到20 wt％，PTLG / PDLA共混物的表观活化能从59.1增至72.1 kJ / mol。 ％，这表明通过添加PDLA提高了PTLG / PDLA共混物的热稳定性。此外，通过CCK-8和活/死染色评估了与人类脂肪干细胞一起培养的PTLG / PDLA共混物的生物相容性。实验结果证明，PTLG / PDLA共混物是一种物理性能优良，细胞毒性极低的生物材料。这表明通过添加PDLA可以增强PTLG / PDLA共混物的热稳定性。此外，通过CCK-8和活/死染色评估了与人类脂肪干细胞一起培养的PTLG / PDLA共混物的生物相容性。实验结果证明，PTLG / PDLA共混物是一种物理性能优良，细胞毒性极低的生物材料。这表明通过添加PDLA可以增强PTLG / PDLA共混物的热稳定性。此外，通过CCK-8和活/死染色评估了与人类脂肪干细胞一起培养的PTLG / PDLA共混物的生物相容性。实验结果证明，PTLG / PDLA共混物是一种物理性能优良，细胞毒性极低的生物材料。