当前位置: X-MOL 学术Lab Anim. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Somatic base editing to model oncogenic drivers in breast cancer.
Lab Animal ( IF 5.9 ) Pub Date : 2020-03-09 , DOI: 10.1038/s41684-020-0510-8
Kirsteen J Campbell 1 , Karen Blyth 1, 2
Affiliation  

Human cancer is a disease of cooperating genetic events that is complex to model in vivo. A new study combines somatic base editing with a mouse model of breast cancer, demonstrating the potential to rapidly investigate the function of disease-specific point mutations.

中文翻译:


体细胞碱基编辑可模拟乳腺癌的致癌驱动因素。



人类癌症是一种遗传事件协同作用的疾病,体内建模非常复杂。一项新研究将体细胞碱基编辑与乳腺癌小鼠模型相结合,证明了快速研究疾病特异性点突变功能的潜力。
更新日期:2020-04-24
down
wechat
bug