当前位置: X-MOL 学术J. Perinatol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Blinded randomized crossover trial: Skin-to-skin care vs. sucrose for preterm neonatal pain.
Journal of Perinatology ( IF 2.4 ) Pub Date : 2020-03-09 , DOI: 10.1038/s41372-020-0638-9
Somashekhar Nimbalkar 1 , Vivek V Shukla 1, 2 , Vishwa Chauhan 1 , Ajay Phatak 1 , Dipen Patel 1 , Apurva Chapla 1 , Archana Nimbalkar 1
Affiliation  

Objective

To compare skin-to-skin care (SSC) and oral sucrose for preterm neonatal pain control.

Methods

Preterm neonates (28–36 weeks gestation) requiring heel-stick were eligible. In group-A, SSC was given 15-min before first heel-stick, and sucrose was given 2-min before second heel-stick. In group-B, the sequence was reversed. Blinded premature infant pain profile (PIPP) score assessment was done at 0, 1, and 5-min of heel-stick by two assessors.

Results

A hundred neonates were enrolled. The inter-rater agreement for the PIPP score was good. The behavior state component was significantly lower in the sucrose group at all assessment points. The mean (SD) difference between 1-min and 0 min was similar [SSC 3.58(3.16) vs. sucrose 4.09(3.82), p = 0.24] between groups. The PIPP score attained baseline values at 5-min in both groups.

Conclusion

Albeit sucrose indicated instantaneous action, SSC and sucrose have comparable clinical efficacy for preterm neonatal pain control. Multisensory stimulation with SSC may result in a higher behavioral state component of the PIPP score.



中文翻译:

盲法随机交叉试验:皮肤对皮肤护理与蔗糖治疗早产新生儿疼痛。

客观的

比较皮肤对皮肤护理 (SSC) 和口服蔗糖在控制早产新生儿疼痛方面的作用。

方法

需要足跟固定的早产新生儿(妊娠 28-36 周)符合条件。在A组中,在第一次足跟刺前15分钟给予SSC,在第二次足跟刺前2分钟给予蔗糖。在 B 组中,顺序颠倒了。盲法早产儿疼痛特征 (PIPP) 评分评估由两名评估员在脚后跟粘连 0、1 和 5 分钟时进行。

结果

招募了一百名新生儿。PIPP 评分的评分者间一致性良好。在所有评估点,蔗糖组的行为状态成分显着降低。1 分钟和 0 分钟之间的平均 (SD) 差异在组间相似 [SSC 3.58(3.16) 与蔗糖 4.09(3.82),p  = 0.24]。两组的 PIPP 评分均在 5 分钟时达到基线值。

结论

尽管蔗糖具有瞬时作用,但 SSC 和蔗糖在控制早产新生儿疼痛方面的临床疗效相当。SSC 的多感官刺激可能会导致 PIPP 评分的行为状态成分更高。

更新日期:2020-04-24
down
wechat
bug