Abstract

A novel nanomagnetic catalyst has been synthesized by immobilization of triethanolamine lactate cellulose with Fe₃O₄ NPs. The prepared catalyst has been used as an efficient and recoverable catalyst for the regioselective synthesis of pyrazolo quinolones by the three-component reaction of dimedone, 5-amino pyrazolone and aromatic aldehydes in ultrasound condition. This economical catalyst provides high yields of products, short experimental time and easy workup for green synthesis of pyrazolo[3,4-b]quinolone compounds. Theoretical studies have been employed to investigate the reaction mechanism by using the B3LYP/6-311G method. Electronic parameters of all components have been determined in order to reorganize the role of components in the reaction mechanism.

Graphic abstract

中文翻译：

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乳酸三乙醇胺负载纳米磁性纤维素：绿色高效合成吡唑并[3,4-b]喹啉的催化剂及理论研究

摘要

通过用Fe ₃ O ₄ NPs固定三乙醇胺乳酸纤维素合成了一种新型的纳米磁性催化剂。所制备的催化剂已被用作高效和可回收的催化剂，用于在超声条件下通过二甲酮，5-氨基吡唑啉酮和芳香醛的三组分反应区域选择性合成吡唑并喹诺酮。这种经济的催化剂为绿色合成吡唑并[3,4- b ]喹诺酮化合物提供了高收率的产品，较短的实验时间并且易于后处理。已经通过理论研究来使用B3LYP / 6-311G方法研究反应机理。已经确定了所有组分的电子参数，以重组组分在反应机理中的作用。

图形摘要