Polyphenols are secondary metabolites widely distributed in many plant foods, such a tea, coffee, chocolate and fruits. The consumption of these compounds is related to the improvement or amelioration of many diseases, including diabetes. Nevertheless, the great barrier to the therapeutic use of polyphenols is the low bioavailability of these compounds once ingested. For that reason, the encapsulation of polyphenols in different matrices may protect them from digestion and improve their release and subsequent absorption to obtain target-specific health effects. Some studies have reported the beneficial effect of encapsulation to increase both bioavailability and bioaccessibility. However, these works have mostly been carried out in vitro and few studies are specifically addressed at improving diabetes. In the current work, an overview of the knowledge related to nanoparticles and their use in the diabetic condition has been reviewed.

中文翻译：

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微囊化是在糖尿病治疗中抵消多酚典型的低生物利用度的工具。

多酚是次生代谢产物，广泛分布在许多植物性食品中，例如茶，咖啡，巧克力和水果。这些化合物的消耗与包括糖尿病在内的许多疾病的改善或改善有关。然而，多酚治疗用途的最大障碍是一旦摄入这些化合物的生物利用度低。因此，将多酚包封在不同的基质中可以保护它们免于消化，并改善其释放和随后的吸收，从而获得目标特异性的健康效果。一些研究报告了包囊增加生物利用度和生物利用度的有益作用。但是，这些工作大部分是在体外进行的，很少有研究专门针对改善糖尿病。在目前的工作中，