Abstract Computed tomography angiography (CTA), a noninvasive imaging procedure, is frequently used for the diagnosis of blood vessel diseases. Pediatric patients are more sensitive to radiation than adults due to their rapidly dividing cells and long life expectancy. Thus, evaluation of pediatric exposure is crucial to ensure that the procedure is justified and the practice is optimized. The objectives of this study were to evaluate pediatric patients' exposure and imaging protocols for different CTA procedures and to estimate the cancer risk incidence. A total of 147 pediatric CTA procedures were performed at King Fahad Medical City using three CT machines (Philips Brilliance CT- 64-slice scanner, Siemens Somatom Definition Flash dual source 128 CT slice scanner and GE 750 HD DISCOVERY dual energy 64 CT slice scanner). The image protocol and patient safety measures were evaluated according to American College of Radiology (ACR) criteria. The Ethics and Research Committee approved the study and informed consent was obtained from children's parents. The mean, standard deviation (sd) and range of patients weight (kg) was 8.1 ± 13.2 (3.5–58.7). The mean, sd, median and range of patient dose (mGy.cm) for circle of willis, carotid arteries, thoracic and abdominal aorta, heart and vessels, renal artery, pulmonary artery, abdominal aorta, thoracic aorta, upper lim and lower limb were 992 ± 798, 759.0 (204–2829), 285 ± 157, 660.0 (56.7–652), 500 ± 457, 210.1 (112–1387), 472 ± 317, 411.4, (175–3909) and 350 ± 346, 589.7 (284–1431), respectively. Pediatric average radiation cancer risk incidence was 36 × 10−4. Patients' doses showed wide variation among the three CT machines and even for the same machine and the same clinical investigation. The dose per procedure is higher compared to previous studies, suggesting that the dose is not yet optimized. Protection of radiosensitive organs is highly recommended for pediatric patients.

中文翻译：

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儿科计算机断层扫描血管造影成像方案和患者辐射暴露的评估

摘要 计算机断层扫描血管造影 (CTA) 是一种无创成像程序，经常用于诊断血管疾病。小儿患者由于细胞分裂迅速且预期寿命长，因此对辐射比成人更敏感。因此，评估儿科暴露对于确保程序合理且实践优化至关重要。本研究的目的是评估儿科患者针对不同 CTA 程序的暴露和成像方案，并估计癌症风险发生率。使用三台 CT 机（飞利浦 Brilliance CT-64 切片扫描仪、西门子 Somatom Definition Flash 双源 128 CT 切片扫描仪和 GE 750 HD DISCOVERY 双能 64 CT 切片扫描仪）在法赫德国王医疗城共进行了 147 次儿科 CTA 手术。 . 根据美国放射学会 (ACR) 标准评估图像协议和患者安全措施。伦理和研究委员会批准了这项研究，并获得了儿童父母的知情同意。患者体重 (kg) 的平均值、标准偏差 (sd) 和范围为 8.1 ± 13.2 (3.5–58.7)。Willis 环、颈动脉、胸腹主动脉、心脏和血管、肾动脉、肺动脉、腹主动脉、胸主动脉、上肢和下肢的平均、sd、中位数和患者剂量范围 (mGy.cm)分别为 992 ± 798, 759.0 (204–2829), 285 ± 157, 660.0 (56.7–652), 500 ± 457, 210.1 (112–1387), 472 ± 317, (107-3) ±3.分别为 589.7 (284–1431)。儿科平均辐射癌症风险发生率为 36 × 10−4。耐心' 剂量在三台 CT 机器之间显示出很大差异，甚至对于同一台机器和相同的临床研究也是如此。与之前的研究相比，每次手术的剂量更高，表明剂量尚未优化。强烈建议儿童患者保护辐射敏感器官。