Abstract Due to its unique properties, silicon nitride has found a wide variety of applications in nanodevice fabrication and biosensing. Self-assembled monolayers of phosphonic acids (SAMPs) can be applied to prepare well-defined organic interfaces suitable to anchor bioreceptor probes with a high surface density on different substrates. In this work, we report on the fabrication of SAMPs functional interfaces on silicon nitride. By using several surface analysis techniques, including contact angle (CA) measurements, atomic force microscopy (AFM), and X-ray photoelectron spectroscopy (XPS), we present a detailed characterization of the morphology, composition, and stability of the functional interface. In addition, we investigate the protective properties of organophosphonate functional interfaces containing only a few ethylene glycol (EG) units per SAMPs building block against non-specific surface binding of charged biomolecules by means of fluorescence spectroscopy.

中文翻译：

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用低聚（乙二醇）封端的有机膦酸酯单层改性氮化硅

摘要 由于其独特的性质，氮化硅在纳米器件制造和生物传感方面有着广泛的应用。自组装单层膦酸 (SAMP) 可用于制备明确定义的有机界面，适用于将具有高表面密度的生物受体探针固定在不同基材上。在这项工作中，我们报告了在氮化硅上制造 SAMP 功能界面。通过使用多种表面分析技术，包括接触角 (CA) 测量、原子力显微镜 (AFM) 和 X 射线光电子能谱 (XPS)，我们详细描述了功能界面的形态、组成和稳定性。此外，