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Temperature-responsive in vitro RNA structurome of Yersinia pseudotuberculosis [Microbiology]
Proceedings of the National Academy of Sciences of the United States of America ( IF 11.1 ) Pub Date : 2016-06-28 10:02:59 , DOI: 10.1073/pnas.1523004113
Francesco Righetti 1 , Aaron M. Nuss 2 , Christian Twittenhoff 1 , Sascha Beele 1 , Kristina Urban 1 , Sebastian Will 3, 4 , Stephan H. Bernhart 3, 4 , Peter F. Stadler 3, 4, 5, 6, 7 , Petra Dersch 2 , Franz Narberhaus 1
Affiliation  

RNA structures are fundamentally important for RNA function. Dynamic, condition-dependent structural changes are able to modulate gene expression as shown for riboswitches and RNA thermometers. By parallel analysis of RNA structures, we mapped the RNA structurome of Yersinia pseudotuberculosis at three different temperatures. This human pathogen is exquisitely responsive to...

中文翻译:

假性耶尔森氏菌的温度响应性体外RNA结构体[微生物学]

RNA结构对于RNA功能至关重要。动态的,取决于条件的结构变化能够调节基因表达,如核糖开关和RNA温度计所示。通过平行分析RNA结构,我们绘制了三种不同温度下假单胞菌耶尔森氏菌的RNA结构图。这种人类病原体对...的反应非常好。
更新日期:2016-07-01
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