Pancreatic cancer is the seventh leading cause of cancer-related deaths worldwide with 432,242 related deaths in 2018. Unlike other cancers, the incidence of pancreatic cancer continues to increase, with little improvement in survival rates. We review the epidemiologic features of pancreatic cancer, covering surveillance and early detection in high-risk persons. We summarize data on worldwide incidence and mortality and analyze the 1975–2016 data from 9 registries of the National Cancer Institute’s Surveillance, Epidemiology, and End Results study, on the overall burden of pancreatic cancer as well as age-, sex-, and race-specific incidence, survival rates and trends. It is important to increase our knowledge of the worldwide and regional epidemiologic features of and risk factors for pancreatic cancer, to identify new approaches for prevention, surveillance, and treatment.

胰腺癌是全球癌症相关死亡的第七大原因，2018 年有 432,242 例相关死亡。与其他癌症不同，胰腺癌的发病率持续增加，但生存率几乎没有改善。我们回顾了胰腺癌的流行病学特征，包括高危人群的监测和早期检测。我们总结了全球发病率和死亡率的数据，并分析了 1975 年至 2016 年国家癌症研究所监测、流行病学和最终结果研究的 9 个登记处的数据，涉及胰腺癌的总体负担以及年龄、性别和种族-具体发病率、存活率和趋势。重要的是增加我们对胰腺癌的全球和区域流行病学特征和危险因素的了解，以确定预防、监测和治疗的新方法。