BACKGROUND Aging is a natural process that, even in the nonattendance of complex diseases, is associated with a numerous behavioral change that attributes reduced muscle mass, power, strength and function. In addition, aging linked to low-grade inflammatory status, characterized by increased plasma concentrations of inflammatory cytokines such as TNF-α and IL-6. Physical exercise is the main non-pharmacological strategy for improving the physical fitness of the aged individuals. However, it is still controversial whether exercise can reduce aging-mediated inflammation. OBJECTIVE To analyze the effects of functional (FT) and traditional (TT) training practice on muscle power and inflammatory profile in physically active older women. METHODS The study has been performed for twenty-six weeks in which twenty-four weeks utilized for training sessions and two weeks for physical and biochemical assessments. Forty-three older women (age FT: 64.25 ± 4.70, range: 60-75; TT: 64.90 ± 3.03, range: 60-71; Control: 65.91 ± 5.79, range: 60-75) were randomly divided into three groups: Functional (FT; n = 16); Traditional (TT; n = 16) training groups; and Control Group (CG; n = 11) respectively. Muscle power tests were performed by push (Bench press) and squatting (Squat) actions. The jumping ability was performed through Counter Movement Jump (CMJ). In addition, isometric strength were assessed by Hand Grip Test. Plasma cytokine concentration was measured using flow cytometry. RESULTS Functional and traditional training sessions subjected to aged women demonstrated a significant enhancement in their physical activity and muscle power. The trained individuals from above two groups showed significant improvements in all analyzed parameters excluding hand-grip. Functional and traditional training exercise reduced the plasma concentrations of TNF-α (FT: p = 0.0001; TT: p = 0.0410) and whereas FT group has reduced IL-6 (p = 0.0072), but did not affect the alterations of pre and post measurements of IL-2 (FT: p = 0.0651; TT: p = 0.2146) and IL-10 values (FT: p = 0.2658; TT: p = 0.3116). There was no significant difference in any of the test parameters between FT and TT groups. CONCLUSION The functional and traditional training practices showed equivalent beneficial outcomes by increasing muscle power and reducing systemic markers associated with inflammation.

中文翻译：

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功能性训练和传统训练可提高老年女性的肌肉力量并减少促炎细胞因子：一项随机对照试验。

背景技术衰老是一个自然过程，即使在未出现复杂疾病的情况下，也与许多行为变化相关，这些行为变化归因于肌肉质量、力量、力量和功能的降低。此外，衰老与低度炎症状态有关，其特征是血浆中炎症细胞因子（如 TNF-α 和 IL-6）的浓度增加。体育锻炼是提高老年人体质的主要非药物策略。然而，运动是否可以减少衰老介导的炎症仍然存在争议。目的 分析功能性 (FT) 和传统 (TT) 训练实践对体力活跃的老年女性肌肉力量和炎症状况的影响。方法 该研究已进行了 26 周，其中 24 周用于培训课程，2 周用于物理和生化评估。43 名老年女性（年龄 FT：64.25 ± 4.70，范围：60-75；TT：64.90 ± 3.03，范围：60-71；对照：65.91 ± 5.79，范围：60-75）被随机分为三组：功能性（FT；n = 16）；传统（TT；n = 16）培训组；和对照组（CG；n = 11）。通过推（卧推）和下蹲（Squat）动作进行肌肉力量测试。跳跃能力是通过反运动跳跃（CMJ）进行的。此外，通过手握测试评估等长力量。使用流式细胞仪测量血浆细胞因子浓度。结果 对老年妇女进行的功能性和传统训练课程显示出她们的身体活动和肌肉力量显着增强。来自上述两组的训练有素的人在所有分析参数（不包括手握力）方面都表现出显着改善。功能性和传统训练运动降低了 TNF-α 的血浆浓度（FT：p = 0.0001；TT：p = 0.0410），而 FT 组降低了 IL-6（p = 0.0072），但不影响前和IL-2（FT：p = 0.0651；TT：p = 0.2146）和 IL-10 值（FT：p = 0.2658；TT：p = 0.3116）的后测量。FT组和TT组之间的任何测试参数均无显着差异。