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Biometric indicators of eyes with occult lens subluxation inducing secondary acute angle closure
BMC Ophthalmology ( IF 1.7 ) Pub Date : 2020-03-05 , DOI: 10.1186/s12886-020-01355-7
Xiaoli Xing , Liangyu Huang , Fang Tian , Yan Zhang , Yingjuan Lv , Wei Liu , Aihua Liu

To compare the anterior biometrics in eyes with secondary acute angle closure induced by occult lens subluxation (ASAC-LS), misdiagnosed as acute primary angle closure (APAC) at the first visit with APAC, chronic primary angle closure glaucoma (CPACG), and cataract. This retrospective case study included 17 eyes with angel closure due to occult LS, who were misdiagnosed as APAC on their first visit, 56 APAC eyes, 54 CPACG eyes, and 56 cataract eyes. Axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), aqueous depth (AD) and lens thickness (LT) were recorded. Lens position (LP), relative lens position (RLP), corrected lens position (CLP) were calculated. Quantitative data were subject to one-way analysis of variance and correlation analysis. Categorical data were analyzed using the chi-squared test. Receiver operating characteristic (ROC) curves were plotted to obtain a suitable cutoff value of ocular biometrics. The ASAC-LS patients had a longer ocular axial length than APAC and CPACG patients. Central corneal thickness of the ASAC-LS patients was not significantly different from APAC patients, but was significantly different from CPACG and cataract patients. The APAC patients had the smallest ACD, while the ASAC-LS patients had the smallest AD. The ASAC-LS patients had the largest lens thickness. According to ROC curve analysis, RLP, ACD, AD, CLP, LP had high power of discrimination. This study revealed that LS secondary PAC patients had a shallower AD, thicker CCT comparing to those of APAC, CPACG and cataract patients. For patients with acute angle-closure glaucoma, it is necessary to exclude lens zonula relaxation. NCT03752710, retrospectively registered.

中文翻译:

隐性晶状体半脱位引起继发性急性闭角的眼睛的生物识别指标

为了比较隐匿性晶状体半脱位(ASAC-LS)引起的继发急性锐角闭合,首次访问时被误诊为急性原发角闭合(APAC),慢性原发性闭角型青光眼(CPACG)和白内障的眼睛的前生物特征。这项回顾性案例研究包括17例因隐匿性LS首次闭诊而被天使闭合的眼睛,56例APAC眼,54例CPACG眼和56例白内障眼。记录轴长(AL),中央角膜厚度(CCT),前房深度(ACD),房水深度(AD)和晶状体厚度(LT)。计算镜片位置(LP),相对镜片位置(RLP),校正镜片位置(CLP)。对定量数据进行方差分析和相关性分析。使用卡方检验分析分类数据。绘制接收器工作特性(ROC)曲线,以获得合适的眼部生物统计学截止值。ASAC-LS患者的眼轴长度比APAC和CPACG患者更长。ASAC-LS患者的中央角膜厚度与APAC患者无显着差异,但与CPACG和白内障患者显着不同。APAC患者的ACD最小,而ASAC-LS患者的AD最小。ASAC-LS患者的晶状体厚度最大。根据ROC曲线分析,RLP,ACD,AD,CLP,LP具有较高的辨别力。这项研究表明,与APAC,CPACG和白内障患者相比,LS继发PAC患者的AD较浅,CCT较厚。对于患有急性闭角型青光眼的患者,有必要排除晶状体小带松弛。NCT03752710,
更新日期:2020-03-06
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