BACKGROUND Hepatitis B virus disease is a potentially life-threatening liver infection and a major global health problem. It causes chronic infection and puts people at high risk of death from cirrhosis and liver cancer. WHO estimated 257 million people are living with hepatitis B virus (HBV) infection and in 2015 alone HBV resulted in to 887,000 deaths globally. We determined the prevalence and associated factors of hepatitis B virus infection among Antenatal Care (ANC) attendees in Gamawa Local Government Area, Bauchi State. METHODS We conducted a descriptive cross-sectional, health facility-based study between March and April 2018. We used systematic random sampling technique to recruit 210 pregnant women aged 15-49 years. With a structured questionnaire, we interviewed the respondents and collected blood sample to test for hepatitis B surface antigen. We calculated frequencies, means, proportions, and tested for associations using Epi Info 7.2 and Microsoft Excel. RESULTS The mean age of respondents was 24.5 ± 6.0 years; 112 (53%) of whom were younger than 25 years. All were married, 183 (87%) had no formal education and up to 190 (90%) were employed. Overall, 14 (6.7%) tested positive for HBsAg; women aged ≥35 years had the highest prevalence (10%). None with tertiary education tested positive and women married before 18 years had 13 (6.2%) prevalence. CONCLUSIONS The prevalence of HBsAg among pregnant women in Gamawa LGA was 6.7% which is quite lower than the national prevalence reported. We recommended improved surveillance of HBV infection and screening of women attending ANC.

中文翻译：

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尼日利亚包奇州加马瓦地方政府地区产前诊所就诊者的乙型肝炎病毒血清阳性率。

背景乙型肝炎病毒疾病是一种可能危及生命的肝脏感染，也是一个主要的全球健康问题。它会导致慢性感染，并使人们面临死于肝硬化和肝癌的高风险。世卫组织估计有 2.57 亿人感染乙型肝炎病毒 (HBV)，仅 2015 年，乙型肝炎就导致全球 887,000 人死亡。我们确定了包奇州加马瓦地方政府区的产前护理 (ANC) 参加者中乙型肝炎病毒感染的患病率和相关因素。方法 我们于 2018 年 3 月至 4 月期间进行了一项基于医疗机构的描述性横断面研究。我们采用系统随机抽样技术招募了 210 名年龄在 15-49 岁之间的孕妇。通过结构化问卷，我们采访了受访者并采集了血液样本来检测乙型肝炎表面抗原。我们使用 Epi Info 7.2 和 Microsoft Excel 计算频率、平均值、比例并测试关联性。结果 受访者的平均年龄为 24.5 ± 6.0 岁；其中 112 人（53%）年龄小于 25 岁。所有人均已婚，183 人（87%）没有受过正规教育，多达 190 人（90%）有工作。总体而言，14 人 (6.7%) HBsAg 检测呈阳性；年龄≥35岁的女性患病率最高（10%）。受过高等教育的人中没有人检测呈阳性，18 岁之前结婚的女性患病率为 13 (6.2%)。结论 Gamawa LGA 孕妇 HBsAg 患病率为 6.7%，远低于全国报告的患病率。我们建议加强对 HBV 感染的监测和对参加 ANC 的女性的筛查。