Distribution of Bibenzyls, Prenyl Bibenzyls, Bis-bibenzyls, and Terpenoids in the Liverwort Genus Radula.,Journal of Natural Products

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Distribution of Bibenzyls, Prenyl Bibenzyls, Bis-bibenzyls, and Terpenoids in the Liverwort Genus Radula.
Journal of Natural Products ( IF 3.3 ) Pub Date : 2020-03-06 , DOI: 10.1021/acs.jnatprod.9b01132
Yoshinori Asakawa ₁ , Fumihiro Nagashima ₁ , Agnieszka Ludwiczuk ₂

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Plants of the Radula genus are chemically very distinct from the other liverworts since they mainly elaborate bibenzyls including bibenzyl cannabinoids and prenyl bibenzyl derivatives, as well as bis-bibenzyls. Several of these components show biological activities such as psychoactivity, vasopressin antagonist, antimicrobial, antifungal, and NO production inhibitory activity, and cytotoxic activity against human cancer cell lines. While distribution of terpenoids in Radula species is in general very limited, some Portuguese species are rich sources of sesquiterpenoids. Among 679 liverwort species so far examined chemically, 264 species contained α-tocopherol, which may play an important antioxidative role for the constituents of oil bodies of liverworts.

中文翻译：

Bibenzyls、Prenyl Bibenzyls、Bis-bibenzyls 和萜类化合物在 Liverwort 属 Radula 中的分布。

所述的植物齿舌属是化学与其他地钱非常明显的，因为它们主要是联苄类阐述包括联苄大麻素和异戊烯基联苄的衍生物，以及双-联苄类。这些成分中的一些显示出生物活性，例如精神活性、加压素拮抗剂、抗微生物、抗真菌和 NO 产生抑制活性，以及对人类癌细胞系的细胞毒活性。虽然Radula物种中萜类化合物的分布通常非常有限，但一些葡萄牙物种是倍半萜类化合物的丰富来源。迄今化学检测的679种地菜中，有264种含有α-生育酚，可能对地菜油体成分具有重要的抗氧化作用。

更新日期：2020-04-24

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