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The Status of Vaccine Development Against the Human Cytomegalovirus
The Journal of Infectious Diseases ( IF 6.4 ) Pub Date : 2020-03-05 , DOI: 10.1093/infdis/jiz447
Stanley A Plotkin 1 , Dai Wang 2 , Abdel Oualim 3 , Don J Diamond 4 , Camille N Kotton 5 , Sally Mossman 6 , Andrea Carfi 7 , David Anderson 8 , Philip R Dormitzer 9
Affiliation  

Numerous candidate vaccines against cytomegalovirus (CMV) infection and disease are in development. Whereas the previous article [1] provides background and opinions about the issues relating to vaccination, this article provides specifics about the vaccines in active development, as reported at a National Institutes of Health-sponsored meeting in Bethesda on September 4–6, 2018. Here, vaccine developers provide synopses of their candidate vaccines to immunize women to protect against congenital CMV disease and to prevent the consequences of CMV disease in recipients of transplanted organs or hematopoietic stem calls. The projects are presented here roughly in the descending order of their stage of development in the opinion of the first author.

中文翻译:

针对人类巨细胞病毒的疫苗开发状况

针对巨细胞病毒(CMV)感染和疾病的多种候选疫苗正在开发中。上一篇文章[1]提供了有关疫苗接种问题的背景和意见,而本文则提供了有关积极开发疫苗的详细信息,正如2018年9月4日至6日在美国贝塞斯达举行的美国国立卫生研究院赞助的会议上报道的那样。在这里,疫苗开发人员提供其候选疫苗的概要,以免疫妇女,以预防先天性巨细胞病毒疾病,并防止巨细胞病毒疾病对移植器官或造血干细胞的接受者造成后果。在第一作者看来,这里的项目大致按其发展阶段的降序排列。
更新日期:2020-03-05
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