Increasing the demands of consumers for organic and safer foods has led to applying new technologies for food preservation. Active packaging (AP) containing natural antimicrobial agents is a good candidate for promoting the shelf life of food products. The efficiency of AP has been enhanced through nanoencapsulation methods, in which antimicrobial-loaded nanocarriers could provide a controlled release of antimicrobial active packaging for keeping the quality of foods during storage. The main objective of this review is to introduce common methods for designing novel encapsulation delivery systems offering controlled release of antimicrobials in the AP systems. The common nanocarriers for enveloping antimicrobial agents are described and the current state of art in the application of nanoencapsulated antimicrobials in development of antimicrobial APs have been summarized and tabulated. Incorporation of a carrier loaded with natural antimicrobial agents is the most effective method for developing AP in the food packaging sector which has become possible by using nanoencapsulated antimicrobials in films or coating structures, instead of using their free form. Nanoencapsulation approaches provide many advantages including protection against environmental stresses, release control, and improving the solubility and absorption of natural antimicrobials in AP, which are the main achievements overcoming the barriers for using natural antimicrobials in food packaging.

消费者对有机食品和更安全食品的需求不断增加，导致了食品保鲜应用新技术。包含天然抗菌剂的主动包装（AP）是延长食品保质期的理想选择。通过纳米封装方法提高了AP的效率，其中加载了抗菌剂的纳米载体可以控制释放抗菌活性包装，从而在存储过程中保持食品质量。这篇综述的主要目的是介绍设计新颖的胶囊递送系统的通用方法，该系统可以在AP系统中控制抗菌剂的释放。描述了用于包封抗微生物剂的常见纳米载体，并且总结并列出了纳米封装的抗微生物剂在抗微生物AP的开发中的应用的当前技术水平。掺入天然抗菌剂的载体是在食品包装领域开发AP的最有效方法，通过在膜或涂层结构中使用纳米囊封的抗菌剂而不是使用游离形式的抗菌剂已成为可能。纳米封装方法具有许多优势，包括保护免受环境压力，控制释放以及提高天然抗菌剂在AP中的溶解度和吸收率，这是克服在食品包装中使用天然抗菌剂的障碍的主要成就。掺入负载有天然抗菌剂的载体是在食品包装领域开发AP的最有效方法，通过在膜或涂层结构中使用纳米囊封的抗菌剂代替游离形式的抗菌剂已成为可能。纳米封装方法具有许多优势，包括保护免受环境压力，控制释放以及提高天然抗菌剂在AP中的溶解度和吸收率，这是克服在食品包装中使用天然抗菌剂的障碍的主要成就。掺入天然抗菌剂的载体是在食品包装领域开发AP的最有效方法，通过在膜或涂层结构中使用纳米囊封的抗菌剂而不是使用游离形式的抗菌剂已成为可能。纳米封装方法具有许多优势，包括保护免受环境压力，控制释放以及提高天然抗菌剂在AP中的溶解度和吸收率，这是克服在食品包装中使用天然抗菌剂的障碍的主要成就。