The existence of “active” and “reserve” stem cell populations in the intestinal epithelium has been debated since 1977. Now in Cell Stem Cell, Murata et al. (2020) show that all intestinal regeneration arises from daughter cell dedifferentiation, marking the coming-of-age of the regenerative stem cell plasticity model.

中文翻译：

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保留更改肠道干细胞模型的权利。

“活动”和“备用”干细胞群体的中肠上皮的存在已辩论自1977年现在，在细胞干细胞，Murata等人。（2020）表明，所有肠道再生都源于子细胞去分化，标志着再生干细胞可塑性模型的成熟。