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Complete Remission of Hypertrophic Discoid Cutaneous Lupus Erythematosus After Treatment of Chronic Hepatitis C With Direct-Acting Antivirals.
JAMA Dermatology ( IF 11.5 ) Pub Date : 2020-04-01 , DOI: 10.1001/jamadermatol.2020.0013 Sumeyre Seda Ertekin 1 , Daniel Morgado-Carrasco 1 , Xavier Forns 2 , José M Mascaró 1
中文翻译：
用直接作用抗病毒药治疗慢性丙型肝炎后肥厚性盘状皮肤性红斑狼疮完全缓解。
更新日期：2020-04-01
JAMA Dermatology ( IF 11.5 ) Pub Date : 2020-04-01 , DOI: 10.1001/jamadermatol.2020.0013 Sumeyre Seda Ertekin 1 , Daniel Morgado-Carrasco 1 , Xavier Forns 2 , José M Mascaró 1
Affiliation
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The pathophysiologic features of lupus erythematosus (LE) are complex, and multiple factors have been suggested, such as genetics, drugs, and infections. Although an association of hepatitis C virus (HCV) infection with LE has not been clearly established, a higher proportion of HCV infection among patients with LE has been reported.1,2 In this observation, we report a case of refractory hypertrophic discoid cutaneous LE with complete remission after the treatment of HCV with direct-acting antivirals (DAAs).
中文翻译：
用直接作用抗病毒药治疗慢性丙型肝炎后肥厚性盘状皮肤性红斑狼疮完全缓解。
红斑狼疮（LE）的病理生理特征很复杂，并且已经提出了多种因素，例如遗传，药物和感染。尽管尚未明确建立丙型肝炎病毒（HCV）感染与LE的关联，但据报道LE患者中HCV感染比例更高。[ 1,2]在此观察中，我们报道了一例难治性肥厚性盘状皮肤性LE，在用直接作用抗病毒药（HCA）治疗HCV后完全缓解。
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