One of the most important blood tests in the field of allergy, mast cell tryptase has numerous diagnostic uses, particularly for anaphylactic reactions and for the diagnosis of mastocytosis. However, there are numerous other non-anaphylactic conditions where clinicians may see elevated serum tryptase (hypertryptasemia) and the practicing clinician ought to be aware of these important differential diagnoses. Such conditions include systemic mastocytosis, hematological malignancies, and chronic kidney disease. This article provides a comprehensive, updated summary on the variety of non-anaphylactic conditions where hypertryptasemia may be seen.

中文翻译：

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非过敏反应病例中血清类胰蛋白酶升高：简要回顾。

作为过敏领域最重要的血液检测之一，肥大细胞类胰蛋白酶具有多种诊断用途，特别是对于过敏反应和肥大细胞增多症的诊​​断。然而，还有许多其他非过敏性疾病，临床医生可能会发现血清类胰蛋白酶升高（高胰蛋白酶血症），临床医生应该注意这些重要的鉴别诊断。此类病症包括系统性肥大细胞增多症、血液系统恶性肿瘤和慢性肾病。本文提供了关于可能出现高胰蛋白酶血症的各种非过敏性疾病的全面、更新的总结。