Millimeter waves (MMW) are broadband frequencies that have recently been used in several applications in wireless communications, medical devices and nonlethal weapons [i.e., the nonlethal weapon, Active Denial Systems, (ADS) operating at 94-95 GHz, CW]. However, little information is available on their potential effects on humans. These radio-frequencies are absorbed and stopped by the first layer of the skin. In this study, we evaluated the effects of 94 GHz on the gene expression of skin cells. Two rat populations consisting of 17 young animals and 14 adults were subjected to chronic long-term 94 GHz MMW exposure. Each group of animals was divided into exposed and sham subgroups. The two independent exposure experiments were conducted for 5 months with rats exposed 3 h per day for 3 days per week to an incident power density of 10 mW/cm2, which corresponded to twice the ICNIRP limit of occupational exposure for humans. At the end of the experiment, skin explants were collected and RNA was extracted. Then, the modifications to the whole gene expression profile were analyzed with a gene expression microarray. Without modification of the animal's temperature, long-term chronic 94 GHz-MMW exposure did not significantly modify the gene expression of the skin on either the young or adult rats.

中文翻译：

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评估94 GHz慢性暴露对体内无毛大鼠皮肤中基因表达的影响。

毫米波（MMW）是宽带频率，最近已在无线通信，医疗设备和非致命武器（即在94-95 GHz CW下运行的非致命武器，主动拒绝系统（ADS））中的几种应用中使用。但是，关于它们对人类的潜在影响的信息很少。这些无线电频率被皮肤的第一层吸收并阻止。在这项研究中，我们评估了94 GHz对皮肤细胞基因表达的影响。由17只年幼动物和14只成年动物组成的两只老鼠种群遭受了长期长期94 GHz MMW暴露。将每组动物分为暴露的和假的亚组。进行了两个独立的暴露实验，为期5个月，大鼠每天暴露3小时，每周暴露3天，入射功率密度为10 mW / cm2，这相当于ICNIRP对人类职业暴露极限的两倍。实验结束时，收集皮肤外植体并提取RNA。然后，用基因表达微阵列分析对整个基因表达谱的修饰。在不改变动物体温的情况下，长期长期暴露于94 GHz-MMW并不会显着改变年轻或成年大鼠皮肤的基因表达。