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Expression of ghrelin and leptin in the chemosensory system of adult zebrafish.
Annals of Anatomy ( IF 2.0 ) Pub Date : 2020-01-21 , DOI: 10.1016/j.aanat.2020.151460
G Montalbano 1 , M Levanti 1 , F Abbate 1 , R Laurà 1 , M Cavallaro 1 , M C Guerrera 1 , A Germanà 1
Affiliation  

Numerous data show that the chemosensory system seems to be modulated by changes in the circulating levels of different molecules such as ghrelin, orexin, leptin, NPY, CCK. The chemosensory system of the zebrafish is represented by the taste buds (skin, oral and oropharyngeal), the olfactory rosette and the solitary chemosensorial cells (SCCs). The purpose of our study was to analyze the distribution of two peripheral hormones such as ghrelin and leptin in the chemosensory organs of the zebrafish. Our results demonstrated the presence of immunoreaction for all antibodies used in the zebrafish chemosensory organs even if with different distribution. In particular, IR was observed for ghrelin in the olfactory rosette while IR for leptin was found in the olfactory rosette, in the skin and oropharyngeal taste buds and in the gills. Both these hormones were detected in the intestine, used as a control.

中文翻译:

生长激素释放肽和瘦素在成年斑马鱼化学感觉系统中的表达。

大量数据表明,化学感应系统似乎受到不同分子(如生长素释放肽,食欲肽,瘦素,NPY,CCK)循环水平变化的调节。斑马鱼的化学感应系统由味蕾(皮肤,口腔和口咽),嗅觉莲座丛和孤立的化学感应细胞(SCC)代表。我们研究的目的是分析两种周围激素(如生长素释放肽和瘦素)在斑马鱼的化学感觉器官中的分布。我们的结果证明,即使分布不同,斑马鱼化学感觉器官中使用的所有抗体均存在免疫反应。特别地,在嗅觉玫瑰花结中观察到了生长素释放肽的IR,而在嗅觉玫瑰花结,皮肤和口咽味蕾中以及the中发现了针对瘦素的IR。
更新日期:2020-01-21
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